Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus

Paula Sundstrom, Jim E. Cutler, Janet F. Staab

Research output: Contribution to journalArticlepeer-review

89 Scopus citations

Abstract

Previous evaluation of HWP1 in systemic candidiasis in CBA/J mice was done with Candida albicans strains with differing genetic locations of URA3 as a result of Ura-blaster mutagenesis. In this study, the presence of HWP1 and the location of URA3 contributed to the severity of murine systemic candidiasis in BALB/c mice.

Original languageEnglish (US)
Pages (from-to)3281-3283
Number of pages3
JournalInfection and immunity
Volume70
Issue number6
DOIs
StatePublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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