Reduction of transient signal oscillations in true-FISP using a linear flip angle series magnetization preparation

Vibhas S. Deshpande, Yiu Cho Chung, Qiang Zhang, Steven M. Shea, Debiao Li

Research output: Contribution to journalArticlepeer-review

77 Scopus citations


An electrocardiogram (ECG)-triggered, magnetization-prepared, segmented, 3D true fast imaging with steady-state precession (true-FISP) sequence with fat saturation was recently proposed for coronary artery imaging. A magnetization preparation scheme consisting of an α/2 radiofrequency (RF) pulse followed by 20 constant flip angle dummy RF cycles was used to reduce signal oscillations in the approach to steady state. However, if large resonance offsets on the order of 70-100 Hz are present, significant magnetization oscillations will still occur during data acquisition, which will result in image ghosting and blurring. The goal of this work was to validate that a linear flip angle (LFA) series can be used during magnetization preparation to reduce these image artifacts. Computer simulations, phantom studies, and coronary artery imaging in healthy volunteers were performed to compare this magnetization preparation scheme with that of an α/2 pulse followed by constant flip angle dummy RF cycles. The results demonstrated substantial reduction in the apparent image artifacts when using linearly increasing flip angles during magnetization preparation.

Original languageEnglish (US)
Pages (from-to)151-157
Number of pages7
JournalMagnetic resonance in medicine
Issue number1
StatePublished - Jan 1 2003


  • Coronary arteries
  • Fast imaging
  • Image artifacts
  • MR angiography
  • Magnetic resonance imaging (MRI)
  • Steady-state free precession (SSFP)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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