Reducing misclassification bias in severe malaria research

Matthew M. Ippolito; Matthew L. Robinson

doi:10.1016/j.xcrm.2022.100789

Reducing misclassification bias in severe malaria research

Matthew M. Ippolito, Matthew L. Robinson

School of Medicine

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.¹ increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification.

Original language	English (US)
Article number	100789
Journal	Cell Reports Medicine
Volume	3
Issue number	10
DOIs	https://doi.org/10.1016/j.xcrm.2022.100789
State	Published - Oct 18 2022

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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title = "Reducing misclassification bias in severe malaria research",

abstract = "By incorporating platelets and PfHRP2 into standard case definitions of severe falciparum malaria, Watson et al.1 increased diagnostic specificity to 93%. The approach trades off sensitivity and might introduce a selection bias but offers a helpful way to handle misclassification.",

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JO - Cell Reports Medicine

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Reducing misclassification bias in severe malaria research

Abstract

ASJC Scopus subject areas

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