Reduced levels of drp1 protect against development of retinal vascular lesions in diabetic retinopathy

Biochemistry, Genetics and Molecular Biology

• Wild Type Mouse 100%
• Streptozotocin 100%
• Pericyte 100%
• Western Blot 50%
• Wild Type 50%
• Caspase 3 50%
• Poly ADP Ribose Polymerase 50%
• Cell Loss 50%
• Mitochondrial Disorder 50%
• Programmed Cell Death 50%
• Glucose 50%

Keyphrases

• Diabetic Retinopathy 100%
• Dynamin-related Protein 1 (Drp1) 100%
• Retinal Vascular Lesions 100%
• Diabetes 36%
• Retina 27%
• Overexpression 27%
• Diabetic 27%
• Diabetic Mice 27%
• Pericyte Loss 18%
• Acellular Capillaries 18%
• Type Control 18%
• Capillary Loss 18%
• Streptozotocin-induced Diabetic Rats 9%
• Protective Effect 9%
• Wild Mice 9%
• Mitochondrial Dysfunction 9%
• Western Blot Analysis 9%
• Retinal Vascular Network 9%
• Cell Loss 9%
• Vascular Cells 9%
• Vascular Lesions 9%
• Apoptotic Genes 9%
• Caspase-3 Activity 9%
• Streptozotocin-induced 9%
• High Glucose 9%
• Cleaved caspase-3 9%
• Promote Apoptosis 9%
• Lesion Characteristics 9%
• Retinal Endothelial Cells 9%
• Cleaved PARP 9%
• Diabetic Retina 9%

Neuroscience

• Diabetes Mellitus 100%
• Diabetic Retinopathy 100%
• Streptozotocin 40%
• Western Blot 20%
• Cell Loss 20%
• Caspase 3 20%
• Poly ADP Ribose Polymerase 20%
• Programmed Cell Death 20%
• Glucose 20%