Abstract
Heart disease is a major cause of death and morbidity worldwide, particularly so in industrialized nations. A major contributor to its varied pathophysiology is abnormal oxidative/reductive and nitrosative stress. While oxidant-scavenging therapies for cardiovascular disease have been disappointing to date, new insights into the precise sources of oxidative/nitrosative stress, its compartmentalized targets, and the modulators designed to control it are paving the way for a very different approach. This issue of the journal presents a Forum highlighting recent work from an international network of investigators that focuses on the role of oxidative/nitrosative stress in the remodeling heart.
Original language | English (US) |
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Pages (from-to) | 1021-1023 |
Number of pages | 3 |
Journal | Antioxidants and Redox Signaling |
Volume | 18 |
Issue number | 9 |
DOIs | |
State | Published - Mar 20 2013 |
ASJC Scopus subject areas
- Biochemistry
- Physiology
- Molecular Biology
- Clinical Biochemistry
- Cell Biology