Recurrent salivary gland cancer

M. Boyd Gillespie, W. Greer Albergotti, David W. Eisele

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Opinion statement: Salivary gland cancer is the most diverse cancer in the body consisting of up to 24 different pathologic subtypes. Although these cancers arise within a common group of glands in the head and neck region, these diverse cancers differ substantially in clinical behavior. As a result, salivary cancers are often categorized as low, intermediate, or high-risk for recurrence and metastasis based on histopathologic subtype and tumor stage. Appropriate risk classification of a given salivary tumor provides a useful guide to the physicians who determine the appropriate treatment regimen. Low-risk tumors can be treated successfully with surgery alone, whereas intermediate and high-risk tumors often require multimodality therapy. Recurrent salivary cancer should be considered high-risk by definition, especially if previously treated with appropriate therapy, and therefore requires aggressive multimodality therapy in order to achieve adequate local control and disease-free survival.

Original languageEnglish (US)
Pages (from-to)58-70
Number of pages13
JournalCurrent treatment options in oncology
Issue number1
StatePublished - Mar 2012
Externally publishedYes


  • Recurrent salivary gland cancer
  • Recurrent salivary gland neoplasm
  • Salivary gland cancer
  • Salivary gland neoplasm
  • Salivary gland surgery
  • Salivary gland tumor

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)


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