TY - JOUR
T1 - Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers
AU - Herridge, Margaret S.
AU - Moss, Marc
AU - Hough, Catherine L.
AU - Hopkins, Ramona O.
AU - Rice, Todd W.
AU - Bienvenu, O. Joseph
AU - Azoulay, Elie
N1 - Publisher Copyright:
© 2016, Springer-Verlag Berlin Heidelberg and ESICM.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Outcomes after acute respiratory distress syndrome (ARDS) are similar to those of other survivors of critical illness and largely affect the nerve, muscle, and central nervous system but also include a constellation of varied physical devastations ranging from contractures and frozen joints to tooth loss and cosmesis. Compromised quality of life is related to a spectrum of impairment of physical, social, emotional, and neurocognitive function and to a much lesser extent discrete pulmonary disability. Intensive care unit-acquired weakness (ICUAW) is ubiquitous and includes contributions from both critical illness polyneuropathy and myopathy, and recovery from these lesions may be incomplete at 5 years after ICU discharge. Cognitive impairment in ARDS survivors ranges from 70 to 100 % at hospital discharge, 46 to 80 % at 1 year, and 20 % at 5 years, and mood disorders including depression and post-traumatic stress disorder (PTSD) are also sustained and prevalent. Robust multidisciplinary and longitudinal interventions that improve these outcomes are still uncertain and data in our literature are conflicting. Studies are needed in family members of ARDS survivors to better understand long-term outcomes of the post-ICU family syndrome and to evaluate how it affects patient recovery.
AB - Outcomes after acute respiratory distress syndrome (ARDS) are similar to those of other survivors of critical illness and largely affect the nerve, muscle, and central nervous system but also include a constellation of varied physical devastations ranging from contractures and frozen joints to tooth loss and cosmesis. Compromised quality of life is related to a spectrum of impairment of physical, social, emotional, and neurocognitive function and to a much lesser extent discrete pulmonary disability. Intensive care unit-acquired weakness (ICUAW) is ubiquitous and includes contributions from both critical illness polyneuropathy and myopathy, and recovery from these lesions may be incomplete at 5 years after ICU discharge. Cognitive impairment in ARDS survivors ranges from 70 to 100 % at hospital discharge, 46 to 80 % at 1 year, and 20 % at 5 years, and mood disorders including depression and post-traumatic stress disorder (PTSD) are also sustained and prevalent. Robust multidisciplinary and longitudinal interventions that improve these outcomes are still uncertain and data in our literature are conflicting. Studies are needed in family members of ARDS survivors to better understand long-term outcomes of the post-ICU family syndrome and to evaluate how it affects patient recovery.
KW - Acute respiratory distress syndrome (ARDS)
KW - Cost
KW - Healthcare utilization
KW - ICU acquired weakness
KW - Neuropsychological
KW - Outcome
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U2 - 10.1007/s00134-016-4321-8
DO - 10.1007/s00134-016-4321-8
M3 - Review article
C2 - 27025938
AN - SCOPUS:84962273344
SN - 0342-4642
VL - 42
SP - 725
EP - 738
JO - Intensive Care Medicine
JF - Intensive Care Medicine
IS - 5
ER -