TY - JOUR
T1 - Recommendations for OCT Angiography Reporting in Retinal Vascular Disease
T2 - A Delphi Approach by International Experts
AU - Munk, Marion R.
AU - Kashani, Amir H.
AU - Tadayoni, Ramin
AU - Korobelnik, Jean Francois
AU - Wolf, Sebastian
AU - Pichi, Francesco
AU - Koh, Adrian
AU - Ishibazawa, Akihiro
AU - Gaudric, Alain
AU - Loewenstein, Anat
AU - Lumbroso, Bruno
AU - Ferrara, Daniela
AU - Sarraf, David
AU - Wong, David T.
AU - Skondra, Dimitra
AU - Rodriguez, Francisco J.
AU - Staurenghi, Giovanni
AU - Pearce, Ian
AU - Kim, Judy E.
AU - Freund, K. Bailey
AU - Parodi, Maurizio Battaglia
AU - Waheed, Nadia K.
AU - Rosen, Richard
AU - Spaide, Richard F.
AU - Nakao, Shintaro
AU - Sadda, Srini Vas
AU - Vujosevic, Stela
AU - Wong, Tien Yin
AU - Murata, Toshinori
AU - Chakravarthy, Usha
AU - Ogura, Yuichiro
AU - Huf, Wolfgang
AU - Tian, Meng
N1 - Publisher Copyright:
© 2022 American Academy of Ophthalmology
PY - 2022/9
Y1 - 2022/9
N2 - Purpose: To develop a consensus nomenclature for reporting OCT angiography (OCTA) findings in retinal vascular disease (e.g., diabetic retinopathy, retinal vein occlusion) by international experts. Design: Delphi-based survey. Subjects, Participants, and/or Controls: Twenty-five retinal vascular disease and OCTA imaging experts. Methods, Intervention, or Testing: A Delphi method of consensus development was used, comprising 2 rounds of online questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-five experts in retinal vascular disease and retinal OCTA imaging were selected to constitute the OCTA Nomenclature in Delphi Study Group for retinal vascular disease. The 4 main areas of consensus were: definition of the parameters of “wide-field (WF)” OCTA, measurement of decreased vascular flow on conventional and WF-OCTA, nomenclature of OCTA findings, and OCTA in retinal vascular disease management and staging. The study end point was defined by the degree of consensus for each question: “strong consensus” was defined as ≥85% agreement, “consensus” as 80% to 84%, and “near consensus” as 70% to 79%. Main Outcome Measures: Consensus and near consensus on OCTA nomenclature in retinal vascular disease. Results: A consensus was reached that a meaningful change in percentage of flow on WF-OCTA imaging should be an increase or decrease ≥30% of the absolute imaged area of flow signal and that a “large area” of WF-OCTA reduced flow signal should also be defined as ≥30% of the absolute imaged area. The presence of new vessels and intraretinal microvascular abnormalities, the foveal avascular zone parameters, the presence and amount of “no-flow areas,” and the assessment of vessel density in various retinal layers should be added for the staging and classification of diabetic retinopathy. Decreased flow ≥30% of the absolute imaged area should define an ischemic central retinal vein occlusion. Several other items did not meet consensus requirements or were rejected in the final discussion round. Conclusions: This study provides international consensus recommendations for reporting OCTA findings in retinal vascular disease, which may help to improve the interpretability and description in clinic and clinical trials. Further validation in these settings is warranted and ongoing. Efforts are continuing to address unresolved questions.
AB - Purpose: To develop a consensus nomenclature for reporting OCT angiography (OCTA) findings in retinal vascular disease (e.g., diabetic retinopathy, retinal vein occlusion) by international experts. Design: Delphi-based survey. Subjects, Participants, and/or Controls: Twenty-five retinal vascular disease and OCTA imaging experts. Methods, Intervention, or Testing: A Delphi method of consensus development was used, comprising 2 rounds of online questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-five experts in retinal vascular disease and retinal OCTA imaging were selected to constitute the OCTA Nomenclature in Delphi Study Group for retinal vascular disease. The 4 main areas of consensus were: definition of the parameters of “wide-field (WF)” OCTA, measurement of decreased vascular flow on conventional and WF-OCTA, nomenclature of OCTA findings, and OCTA in retinal vascular disease management and staging. The study end point was defined by the degree of consensus for each question: “strong consensus” was defined as ≥85% agreement, “consensus” as 80% to 84%, and “near consensus” as 70% to 79%. Main Outcome Measures: Consensus and near consensus on OCTA nomenclature in retinal vascular disease. Results: A consensus was reached that a meaningful change in percentage of flow on WF-OCTA imaging should be an increase or decrease ≥30% of the absolute imaged area of flow signal and that a “large area” of WF-OCTA reduced flow signal should also be defined as ≥30% of the absolute imaged area. The presence of new vessels and intraretinal microvascular abnormalities, the foveal avascular zone parameters, the presence and amount of “no-flow areas,” and the assessment of vessel density in various retinal layers should be added for the staging and classification of diabetic retinopathy. Decreased flow ≥30% of the absolute imaged area should define an ischemic central retinal vein occlusion. Several other items did not meet consensus requirements or were rejected in the final discussion round. Conclusions: This study provides international consensus recommendations for reporting OCTA findings in retinal vascular disease, which may help to improve the interpretability and description in clinic and clinical trials. Further validation in these settings is warranted and ongoing. Efforts are continuing to address unresolved questions.
KW - Consensus approach
KW - Delphi
KW - Nomenclature
KW - OCT angiography
KW - Retinal vascular diseases
KW - diabetic retinopathy
KW - retinal vein occlusion
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U2 - 10.1016/j.oret.2022.02.007
DO - 10.1016/j.oret.2022.02.007
M3 - Article
C2 - 35202889
AN - SCOPUS:85127813934
SN - 2468-7219
VL - 6
SP - 753
EP - 761
JO - Ophthalmology Retina
JF - Ophthalmology Retina
IS - 9
ER -