TY - JOUR
T1 - Real-time monitoring of cardiac regional function using FastHARP MRI and region-of-interest reconstruction
AU - Abd-Elmoniem, Khaled Z.
AU - Sampath, Smita
AU - Osman, Nael F.
AU - Prince, Jerry L.
N1 - Funding Information:
Manuscript received August 22, 2006; revised December 9, 2006. This work was supported by the National Heart, Lung, and Blood Institute under Grant R01 HL47405. J. L. Prince and N. F. Osman are founders of and own stock in Diagnosoft, Inc., a company that has license to the HARP technology. The terms of this arrangement are being managed by the Johns Hopkins University in accordance with its conflict of interest policies. Asterisk indicates corresponding author. *K. Z. Abd-Elmoniem is with the Department of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205 USA (e-mail: [email protected]).
PY - 2007/9
Y1 - 2007/9
N2 - Cardiovascular stress test imaging assists in the diagnosis and monitoring of cardiovascular disease. The procedure can be carried out in a magnetic resonance (MR) scanner using pharmacological agents that mimic the effects of natural exercise. In order to provide real time indication of ischemia, thereby assisting in diagnosis and helping to assure patient safety, it is desirable to have real time monitoring of the myocardial regional function. This paper presents an algorithm for the real time myocardium region-of-interest reconstruction and myocardial strain computation using data acquired from a real time pulse sequence that has been previously reported. The chirp Fourier transform is used for efficient computation, enabling a real-time continuous strain map at a rate of 25 frames/s. Coupled with a real time data path from the scanner to a laptop computer, this algorithm enables real time continuous monitoring of cardiac strain and is targeted for use in the early detection and quantification of ischemia during MR stress tests.
AB - Cardiovascular stress test imaging assists in the diagnosis and monitoring of cardiovascular disease. The procedure can be carried out in a magnetic resonance (MR) scanner using pharmacological agents that mimic the effects of natural exercise. In order to provide real time indication of ischemia, thereby assisting in diagnosis and helping to assure patient safety, it is desirable to have real time monitoring of the myocardial regional function. This paper presents an algorithm for the real time myocardium region-of-interest reconstruction and myocardial strain computation using data acquired from a real time pulse sequence that has been previously reported. The chirp Fourier transform is used for efficient computation, enabling a real-time continuous strain map at a rate of 25 frames/s. Coupled with a real time data path from the scanner to a laptop computer, this algorithm enables real time continuous monitoring of cardiac strain and is targeted for use in the early detection and quantification of ischemia during MR stress tests.
KW - Cardiac motion
KW - FastHARP (HARP-MRI)
KW - Harmonic phase (HARP)
KW - Magnetic resonance (MR) tagging
KW - Myocardial strain
KW - Real-time imaging
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U2 - 10.1109/TBME.2007.891946
DO - 10.1109/TBME.2007.891946
M3 - Article
C2 - 17867357
AN - SCOPUS:34548132111
SN - 0018-9294
VL - 54
SP - 1650
EP - 1656
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 9
ER -