Real-time intraoperative 4D full-range FD-OCT based on the dual graphics processing units architecture for microsurgery guidance

Kang Zhang, Jin U. Kang

Research output: Contribution to journalArticlepeer-review


Real-time 4D full-range complex-conjugate-free Fourier-domain optical coherence tomography (FD-OCT) is implemented using a dual graphics processing units (dual-GPUs) architecture. One GPU is dedicated to the FD-OCT data processing while the second one is used for the volume rendering and display. GPU accelerated non-uniform fast Fourier transform (NUFFT) is also implemented to suppress the side lobes of the point spread function to improve the image quality. Using a 128,000 A-scan/second OCT spectrometer, we obtained 5 volumes/second real-time full-range 3D OCT imaging. A complete micro-manipulation of a phantom using a microsurgical tool is monitored by multiple volume renderings of the same 3D date set with different view angles. Compared to the conventional surgical microscope, this technology would provide the surgeons a more comprehensive spatial view of the microsurgical site and could serve as an effective intraoperative guidance tool.

Original languageEnglish (US)
Pages (from-to)764-770
Number of pages7
JournalBiomedical Optics Express
Issue number4
StatePublished - Apr 1 2011
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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