Real-time imaging of regional myocardial function using fast-SENC

Li Pan, Matthias Stuber, Dara L. Kraitchman, Danielle L. Fritzges, Wesley D. Gilson, Nael F. Osman

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


A technique for fast Imaging of regional myocardial function using a spiral acquisition in combination with strain-encoded (SENC) magnetic resonance imaging (MRI) is presented in this paper. This technique, which is termed fast-SENC, enables scan durations as short as a single heartbeat. A reduced field of view (FOV) without foldover artifacts was achieved by localized SENC, which selectively excited the region around the heart. The two images required for SENC imaging (low- and high-tuning) were acquired in an interleaved fashion throughout the cardiac cycle to further shorten the scan time. Regional circumferential contraction and longitudinal shortening of both the left ventricle (LV) and right ventricle (RV) were examined in long-and short-axis views, respectively. The in vivo results obtained from five human subjects and five infarcted dogs are presented. The results of the fast-SENC technique in a single heartbeat acquisition were comparable to those obtained by conventional SENC in a long acquisition time. Therefore, fast-SENC may prove useful for imaging during stress or arrhythmia.

Original languageEnglish (US)
Pages (from-to)386-395
Number of pages10
JournalMagnetic resonance in medicine
Issue number2
StatePublished - Feb 2006


  • Cardiac MRI
  • Real-time imaging
  • Regional myocardial function
  • SENC
  • Spiral imaging
  • Strain-encoding

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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