Reaction of nitric oxide with hemoglobin

C. Fronticelli, M. Karavitis

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations


The reaction of hemoglobin with nitric oxide has been investigated by recording absorbtion spectra of human hemoglobin in time, in the presence of different ligands. The results are summarized in the figure. They suggest that the combination of the various derivatives of hemoglobin with NO would converge to the formation of methemoglobin [Hb(III)], establishing a redox cycle which depletes the nitric oxide being produced.

Original languageEnglish (US)
Pages (from-to)A99
JournalArtificial Cells, Blood Substitutes, and Immobilization Biotechnology
Issue number5
StatePublished - Nov 1 1994
Externally publishedYes
EventProceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA
Duration: Jul 24 1994Jul 27 1994

ASJC Scopus subject areas

  • Biotechnology
  • Biomedical Engineering


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