Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet

Ruth Schade; Lin Song; Zachary A. Cordner; Hua Ding; Daniel A. Peterson; Timothy H. Moran; Kellie L. Tamashiro; Claire B.de La Serre

doi:10.1016/j.physbeh.2022.113987

Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet

Ruth Schade, Lin Song, Zachary A. Cordner, Hua Ding, Daniel A. Peterson, Timothy H. Moran, Kellie L. Tamashiro, Claire B.de La Serre

Research output: Contribution to journal › Article › peer-review

Abstract

This study assessed the impact of maternal diet during pregnancy versus lactation on offspring gut microbiota. Sprague-Dawley dams were fed high fat (HF) or Chow diets during pregnancy, and their male offspring were raised by a different dam consuming the same or opposite diet (Chow-Chow, Chow-HF, HF-Chow, and HF-HF). Microbiota analysis showed that maternal lactation diet, rather than pregnancy diet, determined offspring microbiota profiles at weaning. Increased abundances of Turicibacter, Staphylococcus, and Ruminococcus were characteristic of chow lactation groups.

Original language	English (US)
Article number	113987
Journal	Physiology and Behavior
Volume	258
DOIs	https://doi.org/10.1016/j.physbeh.2022.113987
State	Published - Jan 1 2023

Keywords

Body weight
Gut microbiota
Lactation
Maternal diet
Obesity
Offspring

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

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10.1016/j.physbeh.2022.113987

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title = "Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet",

abstract = "This study assessed the impact of maternal diet during pregnancy versus lactation on offspring gut microbiota. Sprague-Dawley dams were fed high fat (HF) or Chow diets during pregnancy, and their male offspring were raised by a different dam consuming the same or opposite diet (Chow-Chow, Chow-HF, HF-Chow, and HF-HF). Microbiota analysis showed that maternal lactation diet, rather than pregnancy diet, determined offspring microbiota profiles at weaning. Increased abundances of Turicibacter, Staphylococcus, and Ruminococcus were characteristic of chow lactation groups.",

keywords = "Body weight, Gut microbiota, Lactation, Maternal diet, Obesity, Offspring",

author = "Ruth Schade and Lin Song and Cordner, {Zachary A.} and Hua Ding and Peterson, {Daniel A.} and Moran, {Timothy H.} and Tamashiro, {Kellie L.} and Serre, {Claire B.de La}",

note = "Funding Information: This work was supported by Dalio Philanthropies (T.H.M. and K.L.K.T) and an Exchange Scholarship from the China Scholarship Council of the Ministry of Education of China (L.S.). Publisher Copyright: {\textcopyright} 2022",

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doi = "10.1016/j.physbeh.2022.113987",

language = "English (US)",

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T1 - Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet

AU - Schade, Ruth

AU - Song, Lin

AU - Cordner, Zachary A.

AU - Ding, Hua

AU - Peterson, Daniel A.

AU - Moran, Timothy H.

AU - Tamashiro, Kellie L.

AU - Serre, Claire B.de La

N1 - Funding Information: This work was supported by Dalio Philanthropies (T.H.M. and K.L.K.T) and an Exchange Scholarship from the China Scholarship Council of the Ministry of Education of China (L.S.). Publisher Copyright: © 2022

PY - 2023/1/1

Y1 - 2023/1/1

N2 - This study assessed the impact of maternal diet during pregnancy versus lactation on offspring gut microbiota. Sprague-Dawley dams were fed high fat (HF) or Chow diets during pregnancy, and their male offspring were raised by a different dam consuming the same or opposite diet (Chow-Chow, Chow-HF, HF-Chow, and HF-HF). Microbiota analysis showed that maternal lactation diet, rather than pregnancy diet, determined offspring microbiota profiles at weaning. Increased abundances of Turicibacter, Staphylococcus, and Ruminococcus were characteristic of chow lactation groups.

AB - This study assessed the impact of maternal diet during pregnancy versus lactation on offspring gut microbiota. Sprague-Dawley dams were fed high fat (HF) or Chow diets during pregnancy, and their male offspring were raised by a different dam consuming the same or opposite diet (Chow-Chow, Chow-HF, HF-Chow, and HF-HF). Microbiota analysis showed that maternal lactation diet, rather than pregnancy diet, determined offspring microbiota profiles at weaning. Increased abundances of Turicibacter, Staphylococcus, and Ruminococcus were characteristic of chow lactation groups.

KW - Body weight

KW - Gut microbiota

KW - Lactation

KW - Maternal diet

KW - Obesity

KW - Offspring

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JO - Physiology and Behavior

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ER -

Rat offspring's microbiota composition is predominantly shaped by the postnatal maternal diet rather than prenatal diet

Abstract

Keywords

ASJC Scopus subject areas

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