High throughput laser desorption (LD) mass spectrometry was used to study the rapid detection of malaria parasites in blood. The LD mass spectra of intact heme contained a series of structure-specific ions and signal intensities were quantitatively correlated with the sample parasitemia. Pulsed ion extraction was optimized for ion focusing and transmission at m/z 1200. A unique time of flight (TOF) multi-array system for increasing the throughput of blood screening for malaria was tested by simultaneous acquisition and analysis of multiple mass spectra.
|Number of pages
|Published - 2002
|Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002 → Jun 6 2002
|Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
|6/2/02 → 6/6/02
ASJC Scopus subject areas