Radionuclide imaging metabolic activity of brown adipose tissue in a patient with pheochromocytoma

Kazuki Fukuchi, M. Tatsumi, Y. Ishida, N. Oku, J. Hatazawa, R. L. Wahl

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


We describe a patient with extra-adrenal pheochmmocytoma and high plasma norepinephrine levels. Radionuclide images of this patient obtained using 18F-fluorodeoxyglucose and 123I-metaiodobenzylguanidine revealed bilateral tracer accumulation in the shoulder and lower neck. The regions of radiotracer uptake corresponded to the location of human brown adipose tissue (BAT). Excessive sympathetic stimulation by high circulating catecholamine concentrations augmented the metabolic activity and tracer uptake in the BAT. This study showed that radionuclide imaging can noninvasively visualize human BAT in terms of metabolic and functional activity.

Original languageEnglish (US)
Pages (from-to)601-603
Number of pages3
JournalExperimental and Clinical Endocrinology and Diabetes
Issue number10
StatePublished - Nov 2004
Externally publishedYes


  • Fat
  • Pheochromocytoma
  • Positron emission tomography (PET)
  • Radionuclide imaging

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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