Radiation-induced optic neuropathy: A review

Research output: Contribution to journalReview articlepeer-review

Abstract

Radiation is a commonly used treatment modality for head and neck as well as CNS tumours, both benign and malignant. As newer oncology treatments such as immunotherapies allow for longer survival, complications from radiation therapy are becoming more common. Radiation-induced optic neuropathy is a feared complication due to rapid onset and potential for severe and bilateral vision loss. Careful monitoring of high-risk patients and early recognition are crucial for initiating treatment to prevent severe vision loss due to a narrow therapeutic window. This review discusses presentation, aetiology, recent advances in diagnosis using innovative MRI techniques and best practice treatment options based on the most recent evidence-based medicine.

Original languageEnglish (US)
Pages (from-to)743-749
Number of pages7
JournalBritish Journal of Ophthalmology
Volume107
Issue number6
DOIs
StatePublished - Jun 1 2023

Keywords

  • Degeneration
  • Diagnostic tests/Investigation
  • Drugs
  • Imaging
  • Optic Nerve

ASJC Scopus subject areas

  • Sensory Systems
  • Cellular and Molecular Neuroscience
  • Ophthalmology

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