Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies

Keyphrases

• Gleason Grading 100%
• Prostate Needle Biopsy 100%
• GSTP1 100%
• Tumor Volume 100%
• Methylation Status 100%
• Methylation 76%
• Prostate Cancer 17%
• Prostate Tissue 17%
• Methylation Assay 17%
• Prostate 11%
• Spearman Correlation Coefficient 11%
• Benign Prostate Disease 11%
• Needle Core 11%
• Tumor 5%
• Prognostic Significance 5%
• Prostate Biopsy 5%
• Gene Promoter 5%
• Polymerase Chain Reaction 5%
• GSTP1 Gene 5%
• Pathological Diagnosis 5%
• Epigenetic Modification 5%
• Formalin-fixed 5%
• Patients with Prostate Cancer 5%
• Reaction-based 5%
• Formalin-fixed Paraffin-embedded Tissue 5%
• Multiple Linear Regression Model 5%
• Histological Evaluation 5%
• Methylation-specific Polymerase Chain Reaction 5%
• Extracted DNA 5%
• Accurate Discrimination 5%
• Fluorogenic 5%
• Cancer Biopsy 5%
• Cancer Volume 5%

Medicine and Dentistry

• Neoplasm 100%
• Methylation 100%
• Gleason Score 100%
• Needle Biopsy 100%
• Prostate Cancer 20%
• Malignant Neoplasm 20%
• Biopsy 15%
• Prostate Tissue 15%
• Polymerase Chain Reaction 10%
• Formaldehyde 10%
• Histology 5%
• Multiple Linear Regression Analysis 5%
• Sensitivity and Specificity 5%
• Prostate Biopsy 5%
• Promoter Region 5%
• Tumor Biopsy 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Neoplasm 100%
• Gleason Score 100%
• Malignant Neoplasm 71%
• Prostate Cancer 57%
• Formaldehyde 28%