In this study the authors wish to report that during the stages of the estrous cycle there is a significant modulation of the immune capacity of splenic lymphocytes from BALB/c female mice in response to T and B cell mitogens and to antigenic challenge with sheep erythrocytes. Of interest is the striking parallelism between immune reactivity, as discerned by us, and the previously reported biphasic changes in pregnenolone levels during the estrous cycle.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of Immunology|
|State||Published - 1978|
ASJC Scopus subject areas
- Immunology and Allergy