Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy

B. M.W. Tsui; X. D. Zhao; G. K. Gregoriou; D. S. Lalush; E. C. Frey; R. E. Johnston; W. H. McCartney

Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy

B. M.W. Tsui, X. D. Zhao, G. K. Gregoriou, D. S. Lalush, E. C. Frey, R. E. Johnston, W. H. McCartney

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Patient anatomy has complicated effects on cardiac SPECT images. We investigated reconstruction methods which substantially reduced these effects for improved image quality. A 3D MCAT (mathematical cardiac-torso) phantom which models the anatomical structures in the thorax region were used in the study. The phantom was modified to simulate variations in patient anatomy including regions of natural thinning along the myocardium, body size, diaphragmatic shape, gender, and size and shape of breasts for female. Distributions of attenuation coefficients and Tl-201 uptake in different organs in a normal patient were also simulated. Emission projection data were generated from the phantoms including effects of attenuation and detector response. We demonstrated the attenuation-induced artifacts caused by patient anatomy in the conventional FBP reconstructed images. Accurate attenuation compensation using iterative reconstruction algorithms and attenuation maps substantially reduced the image artifacts and improved quantitative accuracy. We conclude that reconstruction methods which accurately compensate for non-uniform attenuation can substantially reduce image degradation caused by variations in patient anatomy in cardiac SPECT.

Original language	English (US)
Title of host publication	IEEE Nuclear Science Symposium & Medical Imaging Conference
Publisher	Publ by IEEE
Pages	1444-1448
Number of pages	5
Edition	pt 3
ISBN (Print)	0780314875
State	Published - 1994
Externally published	Yes
Event	Proceedings of the 1993 IEEE Nuclear Science Symposium & Medical Imaging Conference - San Francisco, CA, USA Duration: Oct 30 1993 → Nov 6 1993

Publication series

Name	IEEE Nuclear Science Symposium & Medical Imaging Conference
Number	pt 3

Other

Other	Proceedings of the 1993 IEEE Nuclear Science Symposium & Medical Imaging Conference
City	San Francisco, CA, USA
Period	10/30/93 → 11/6/93

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Cite this

Tsui, B. M. W., Zhao, X. D., Gregoriou, G. K., Lalush, D. S., Frey, E. C., Johnston, R. E., & McCartney, W. H. (1994). Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy. In IEEE Nuclear Science Symposium & Medical Imaging Conference (pt 3 ed., pp. 1444-1448). (IEEE Nuclear Science Symposium & Medical Imaging Conference; No. pt 3). Publ by IEEE.

Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy. / Tsui, B. M.W.; Zhao, X. D.; Gregoriou, G. K. et al.
IEEE Nuclear Science Symposium & Medical Imaging Conference. pt 3. ed. Publ by IEEE, 1994. p. 1444-1448 (IEEE Nuclear Science Symposium & Medical Imaging Conference; No. pt 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Tsui, BMW, Zhao, XD, Gregoriou, GK, Lalush, DS, Frey, EC, Johnston, RE & McCartney, WH 1994, Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy. in IEEE Nuclear Science Symposium & Medical Imaging Conference. pt 3 edn, IEEE Nuclear Science Symposium & Medical Imaging Conference, no. pt 3, Publ by IEEE, pp. 1444-1448, Proceedings of the 1993 IEEE Nuclear Science Symposium & Medical Imaging Conference, San Francisco, CA, USA, 10/30/93.

@inproceedings{130b2393a9f841278fca948ff42dcbcd,

title = "Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy",

abstract = "Patient anatomy has complicated effects on cardiac SPECT images. We investigated reconstruction methods which substantially reduced these effects for improved image quality. A 3D MCAT (mathematical cardiac-torso) phantom which models the anatomical structures in the thorax region were used in the study. The phantom was modified to simulate variations in patient anatomy including regions of natural thinning along the myocardium, body size, diaphragmatic shape, gender, and size and shape of breasts for female. Distributions of attenuation coefficients and Tl-201 uptake in different organs in a normal patient were also simulated. Emission projection data were generated from the phantoms including effects of attenuation and detector response. We demonstrated the attenuation-induced artifacts caused by patient anatomy in the conventional FBP reconstructed images. Accurate attenuation compensation using iterative reconstruction algorithms and attenuation maps substantially reduced the image artifacts and improved quantitative accuracy. We conclude that reconstruction methods which accurately compensate for non-uniform attenuation can substantially reduce image degradation caused by variations in patient anatomy in cardiac SPECT.",

author = "Tsui, {B. M.W.} and Zhao, {X. D.} and Gregoriou, {G. K.} and Lalush, {D. S.} and Frey, {E. C.} and Johnston, {R. E.} and McCartney, {W. H.}",

note = "Copyright: Copyright 2004 Elsevier B.V., All rights reserved.; Proceedings of the 1993 IEEE Nuclear Science Symposium & Medical Imaging Conference ; Conference date: 30-10-1993 Through 06-11-1993",

year = "1994",

language = "English (US)",

isbn = "0780314875",

series = "IEEE Nuclear Science Symposium & Medical Imaging Conference",

publisher = "Publ by IEEE",

number = "pt 3",

pages = "1444--1448",

booktitle = "IEEE Nuclear Science Symposium & Medical Imaging Conference",

edition = "pt 3",

}

TY - GEN

T1 - Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy

AU - Tsui, B. M.W.

AU - Zhao, X. D.

AU - Gregoriou, G. K.

AU - Lalush, D. S.

AU - Frey, E. C.

AU - Johnston, R. E.

AU - McCartney, W. H.

PY - 1994

Y1 - 1994

N2 - Patient anatomy has complicated effects on cardiac SPECT images. We investigated reconstruction methods which substantially reduced these effects for improved image quality. A 3D MCAT (mathematical cardiac-torso) phantom which models the anatomical structures in the thorax region were used in the study. The phantom was modified to simulate variations in patient anatomy including regions of natural thinning along the myocardium, body size, diaphragmatic shape, gender, and size and shape of breasts for female. Distributions of attenuation coefficients and Tl-201 uptake in different organs in a normal patient were also simulated. Emission projection data were generated from the phantoms including effects of attenuation and detector response. We demonstrated the attenuation-induced artifacts caused by patient anatomy in the conventional FBP reconstructed images. Accurate attenuation compensation using iterative reconstruction algorithms and attenuation maps substantially reduced the image artifacts and improved quantitative accuracy. We conclude that reconstruction methods which accurately compensate for non-uniform attenuation can substantially reduce image degradation caused by variations in patient anatomy in cardiac SPECT.

AB - Patient anatomy has complicated effects on cardiac SPECT images. We investigated reconstruction methods which substantially reduced these effects for improved image quality. A 3D MCAT (mathematical cardiac-torso) phantom which models the anatomical structures in the thorax region were used in the study. The phantom was modified to simulate variations in patient anatomy including regions of natural thinning along the myocardium, body size, diaphragmatic shape, gender, and size and shape of breasts for female. Distributions of attenuation coefficients and Tl-201 uptake in different organs in a normal patient were also simulated. Emission projection data were generated from the phantoms including effects of attenuation and detector response. We demonstrated the attenuation-induced artifacts caused by patient anatomy in the conventional FBP reconstructed images. Accurate attenuation compensation using iterative reconstruction algorithms and attenuation maps substantially reduced the image artifacts and improved quantitative accuracy. We conclude that reconstruction methods which accurately compensate for non-uniform attenuation can substantially reduce image degradation caused by variations in patient anatomy in cardiac SPECT.

UR - http://www.scopus.com/inward/record.url?scp=0028196456&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028196456&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0028196456

SN - 0780314875

T3 - IEEE Nuclear Science Symposium & Medical Imaging Conference

SP - 1444

EP - 1448

BT - IEEE Nuclear Science Symposium & Medical Imaging Conference

PB - Publ by IEEE

T2 - Proceedings of the 1993 IEEE Nuclear Science Symposium & Medical Imaging Conference

Y2 - 30 October 1993 through 6 November 1993

ER -

Quantitative cardiac SPECT reconstruction with reduced image degradation due to patient anatomy

Abstract

Publication series

Other

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this