TY - JOUR
T1 - Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures
AU - Black, Betty E
AU - Johnston, Deirdre
AU - Morrison, Ann
AU - Rabins, Peter V.
AU - Lyketsos, Constantine G.
AU - Samus, Quincy M.
N1 - Funding Information:
Acknowledgments The authors would like to especially thank Mr. Leroy Hoffberger and the study participants and their study partners for their contributions to this work. We would also like to thank our community partners including Jewish Community Services, Levin-dale Hebrew Geriatric Center, and the Alzheimer’s Association Greater Maryland Chapter. This work was supported financially by the following organizations and individuals: The ASSOCIATED Jewish Community Federation of Baltimore, Harry & Jeannette Weinberg Foundation, Leonard & Helen R. Stulman Charitable Foundation, The Hoffberger Foundation, Hoffberger Family Fund, Leroy Hoffberger, David & Barbara B. Hirschhorn Foundation, Irving & Lois Blum Foundation, Leonor & Marc Blum, Lois Blum Feinblatt, Meyerhoff Family Charitable Foundations, and the Baltimore County Department of Aging. This work was also supported financially by Grant # K01MH085142 from the National Institute of Mental Health.
PY - 2012/10
Y1 - 2012/10
N2 - Purpose: To identify correlates of self-rated and caregiver-rated quality of life (QOL) in community-residing persons with dementia (PWD) for intervention development. Methods: Cross-sectional data of 254 PWD and their caregivers participating in a clinical trial were derived from in-home assessments. Self-rated QOL was measured with the Quality of Life-Alzheimer Disease (QOL-AD) scale, and caregiver-rated QOL was measured using the QOL-AD and Alzheimer Disease-Related Quality of Life (ADRQL) scales. Multivariate modeling identified correlates of the PWD' QOL. Results: Self-rated QOL was related significantly to participant race, unmet needs, depression, and total medications. Caregiver-rated QOL-AD scores were significantly associated with participant function, unmet needs, depression, and health problems and with caregiver burden and self-rated health. Significant correlates of ADRQL scores included neuropsychiatric symptom severity, functional and cognitive impairment, and caregiver burden and depression. Conclusions: Correlates of QOL in community-residing PWD depend on who rates the PWD's QOL and which measure is used. Addressing health problems, medication use, and dementia-related unmet needs, reducing functional dependency, and treating neuropsychiatric symptoms in PWD, while reducing caregiver burden and depression, may maximize QOL in those with dementia.
AB - Purpose: To identify correlates of self-rated and caregiver-rated quality of life (QOL) in community-residing persons with dementia (PWD) for intervention development. Methods: Cross-sectional data of 254 PWD and their caregivers participating in a clinical trial were derived from in-home assessments. Self-rated QOL was measured with the Quality of Life-Alzheimer Disease (QOL-AD) scale, and caregiver-rated QOL was measured using the QOL-AD and Alzheimer Disease-Related Quality of Life (ADRQL) scales. Multivariate modeling identified correlates of the PWD' QOL. Results: Self-rated QOL was related significantly to participant race, unmet needs, depression, and total medications. Caregiver-rated QOL-AD scores were significantly associated with participant function, unmet needs, depression, and health problems and with caregiver burden and self-rated health. Significant correlates of ADRQL scores included neuropsychiatric symptom severity, functional and cognitive impairment, and caregiver burden and depression. Conclusions: Correlates of QOL in community-residing PWD depend on who rates the PWD's QOL and which measure is used. Addressing health problems, medication use, and dementia-related unmet needs, reducing functional dependency, and treating neuropsychiatric symptoms in PWD, while reducing caregiver burden and depression, may maximize QOL in those with dementia.
KW - Caregivers
KW - Community-based participatory research
KW - Dementia
KW - Health services needs and demands
KW - Quality of life
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U2 - 10.1007/s11136-011-0044-z
DO - 10.1007/s11136-011-0044-z
M3 - Article
C2 - 22038392
AN - SCOPUS:84867069685
SN - 0962-9343
VL - 21
SP - 1379
EP - 1389
JO - Quality of Life Research
JF - Quality of Life Research
IS - 8
ER -