Quality of life assessment of patients in extremity sarcoma clinical trials

Paul H. Sugarbaker, Ivan Barofsky, Steven A. Rosenberg, Fred J. Gianola

Research output: Contribution to journalArticlepeer-review

277 Scopus citations


Twenty-six patients with soft tissue sarcoma who participated in a randomized controlled clinical trial were studied to compare the impact of treatments on quality of life. Patients were treated with amputation plus chemotherapy or with limb-sparing surgery plus radiation therapy plus chemotherapy. After completion of treatments, when the patients' physical status had stabilized, a "Quality of Life Assessment" was administered. It consisted of the Psychosocial Adjustment to Illness Scale, the Sickness Impact Profile, the Barthel Function Scale, the Katz Activities of Daily Living Scale, and an economic assessment. In addition, clinical assessments of mobility, pain, sexual relationships, and treatment trauma were obtained. Analysis of these assessments indicated that our hypothesis that limb-sparing surgery plus irradiation would provide improved quality of life when compared to amputation was not substantiated.

Original languageEnglish (US)
Pages (from-to)17-23
Number of pages7
Issue number1
StatePublished - Jan 1982

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Quality of life assessment of patients in extremity sarcoma clinical trials'. Together they form a unique fingerprint.

Cite this