Recent years have seen a dramatic broadening of the implications for measuring quality of life (QL) in lung surgery. Beyond the traditional impacts on pulmonary function or survival, one must now consider the role of adjuvant (postoperative) and neoadjuvant (preoperative) radiation and chemotherapy. A number of reasonable QL instruments now exist and can be utilized if careful attention is paid to logistical and operational issues. In 1985, the Lung Cancer Study Group initiated a trial of the Functional Living Index - Cancer (FLIC) in patients across a wide variety of trials. QL was found to be a significant prognostic factor for recurrence and survival and to be independent of Karnofsky performance status. The total FLIC score was superior to any individual time or factor score. Preliminary analyses of changes in QL over time, in studies comparing chemotherapy with control, show virtually no impact of the chemotherapy on QL.
|Original language||English (US)|
|Number of pages||5|
|State||Published - 1991|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine