TY - JOUR
T1 - Quality assessment of the guidelines on cystic neoplasms of the pancreas
AU - Falconi, Massimo
AU - Crippa, Stefano
AU - Chari, Suresh
AU - Conlon, Kevin
AU - Kim, Sun Whe
AU - Levy, Philippe
AU - Tanaka, Masao
AU - Werner, Jens
AU - Wolfgang, Christopher L.
AU - Pezzilli, Raffaele
AU - Castillo, Carlos Fernandez Del
N1 - Publisher Copyright:
Copyright © 2015, IAP and EPC. Published by Elsevier India, a division of Reed Elsevier India Pvt. Ltd. All rights reserved.
PY - 2015/9
Y1 - 2015/9
N2 - Background Though cystic pancreatic neoplasms (CPNs) are being increasingly detected, their evaluation and management are still debated and have lead to publication of multiple guidelines for diagnostic work-up, indications for resection, and non-operative management with follow-up strategies of CPNs. Aims To analyze available guidelines in order to evaluate their overall quality and clinical applicability, indications for surgical resection and its extent, modalities and timing of follow-up when non-operative management is indicated. Methods After a systematic search of the English literature, we selected eight guidelines for assessment according to the Appraisal of Guidelines, Research and Evaluation in Europe (AGREE) II instrument. Results One guideline received the lower AGREE score regarding the "scope and purpose", "rigor of development" and "clarity and presentation" domains, whereas one received the best score for "stakeholder involvement" domain. No differences were found among different guidelines regarding the "applicability". The overall quality assessment score showed that only two guidelines were significantly lower than the others. According to the practical utilization recommendation score, four guidelines were considered as having full applicability in clinical practice. Conclusion Existing guidelines provide adequate guidance, at least with the present knowledge, for the management of cystic pancreatic lesions; however, not any one was satisfactory to all aspects related to the management of CPN. An update of the existing guidelines should be considered if and when more evidence-based data are available.
AB - Background Though cystic pancreatic neoplasms (CPNs) are being increasingly detected, their evaluation and management are still debated and have lead to publication of multiple guidelines for diagnostic work-up, indications for resection, and non-operative management with follow-up strategies of CPNs. Aims To analyze available guidelines in order to evaluate their overall quality and clinical applicability, indications for surgical resection and its extent, modalities and timing of follow-up when non-operative management is indicated. Methods After a systematic search of the English literature, we selected eight guidelines for assessment according to the Appraisal of Guidelines, Research and Evaluation in Europe (AGREE) II instrument. Results One guideline received the lower AGREE score regarding the "scope and purpose", "rigor of development" and "clarity and presentation" domains, whereas one received the best score for "stakeholder involvement" domain. No differences were found among different guidelines regarding the "applicability". The overall quality assessment score showed that only two guidelines were significantly lower than the others. According to the practical utilization recommendation score, four guidelines were considered as having full applicability in clinical practice. Conclusion Existing guidelines provide adequate guidance, at least with the present knowledge, for the management of cystic pancreatic lesions; however, not any one was satisfactory to all aspects related to the management of CPN. An update of the existing guidelines should be considered if and when more evidence-based data are available.
KW - ADAPTE method
KW - AGREE instrument
KW - Diagnosis
KW - Follow-up
KW - Mucinous cystic neoplasm
KW - Pancreatic cystic lesions
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U2 - 10.1016/j.pan.2015.05.478
DO - 10.1016/j.pan.2015.05.478
M3 - Review article
C2 - 26100659
AN - SCOPUS:84943660271
SN - 1424-3903
VL - 15
SP - 463
EP - 469
JO - Pancreatology
JF - Pancreatology
IS - 5
ER -