Quality and safety in obesity surgery-15 years of Roux-en-Y gastric bypass outcomes from a longitudinal database

Anna C. Weiss, Ralitza Parina, Santiago Horgan, Mark Talamini, David C. Chang, Bryan Sandler

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background: Most population-based studies lack long-term data, making the reporting of true mortality and outcome rates difficult. An accurate estimate of these rates in a high-risk population is critical for obtaining informed consent, especially for an elective procedure such as Roux-en-Y gastric bypass (RYGB). Objectives: To examine the longitudinal outcomes of RYGB. Setting: The California Office of Statewide Health Planning and Development (OSHPD) longitudinal database. Methods: The OSHPD longitudinal database was queried for patients who underwent RYGB between 1995 and 2009. The primary outcome was mortality rates at 1, 5, and 10 years. Secondary outcomes were marginal ulcer and reoperation. The Cox hazard proportional analysis was used to determine adjusted survival and long-term outcomes for laparoscopic RYGB compared with open RYGB. Results: The study included 129,432 RYGB patients. Rates of laparoscopy increased from 3% to 35% from 1995 to 2004 and then steeply increased to 80% in 2005 and to 93% in 2009. Overall mortality rate at 1, 5, and 10 years was 2.2%, 4.4%, and 8.1%, respectively; the rates of marginal ulcer were .3%, .7%, and 1%, respectively; and the reoperation rates were .3%, .8%, and 1.2%, respectively. Predictors of poor outcomes were male gender, age, smoking, alcohol, Medicare, Medi-Cal insurance, and Asian or Native American race. The laparoscopic approach was protective against death (hazard ratio [HR] 95% confidence interval [95%CI]: .63[.58-.69]) and long-term complications (HR .78[.72-.85]). Conclusions: This longitudinal population study showed high rates of mortality following RYGB, with improved long-term outcomes when the laparoscopic approach was used.

Original languageEnglish (US)
Pages (from-to)33-40
Number of pages8
JournalSurgery for Obesity and Related Diseases
Issue number1
StatePublished - Jan 2016


  • Gastric bypass outcomes
  • Longitudinal laparoscopic outcomes
  • Roux-en-Y gastric bypass

ASJC Scopus subject areas

  • Surgery


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