Putting the Brakes on Cytokinesis with α-Actinin

Elizabeth M. Reichl; Douglas N. Robinson

doi:10.1016/j.devcel.2007.09.010

Putting the Brakes on Cytokinesis with α-Actinin

Elizabeth M. Reichl, Douglas N. Robinson

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

11 Scopus citations

Abstract

Although signal transduction pathways provide spatiotemporal control of cytokinesis, additional regulation likely occurs through complex cytoskeletal network interactions. In this issue of Developmental Cell, Mukhina et al. (2007) show that myosin-II modulates the cortical lifetime of the actin crosslinker α-actinin, which in turn tunes actin filament dynamics, thereby controlling furrow ingression.

Original language	English (US)
Pages (from-to)	460-462
Number of pages	3
Journal	Developmental Cell
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/j.devcel.2007.09.010
State	Published - Oct 9 2007

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

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10.1016/j.devcel.2007.09.010

Cite this

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title = "Putting the Brakes on Cytokinesis with α-Actinin",

abstract = "Although signal transduction pathways provide spatiotemporal control of cytokinesis, additional regulation likely occurs through complex cytoskeletal network interactions. In this issue of Developmental Cell, Mukhina et al. (2007) show that myosin-II modulates the cortical lifetime of the actin crosslinker α-actinin, which in turn tunes actin filament dynamics, thereby controlling furrow ingression.",

author = "Reichl, {Elizabeth M.} and Robinson, {Douglas N.}",

year = "2007",

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T1 - Putting the Brakes on Cytokinesis with α-Actinin

AU - Reichl, Elizabeth M.

AU - Robinson, Douglas N.

PY - 2007/10/9

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N2 - Although signal transduction pathways provide spatiotemporal control of cytokinesis, additional regulation likely occurs through complex cytoskeletal network interactions. In this issue of Developmental Cell, Mukhina et al. (2007) show that myosin-II modulates the cortical lifetime of the actin crosslinker α-actinin, which in turn tunes actin filament dynamics, thereby controlling furrow ingression.

AB - Although signal transduction pathways provide spatiotemporal control of cytokinesis, additional regulation likely occurs through complex cytoskeletal network interactions. In this issue of Developmental Cell, Mukhina et al. (2007) show that myosin-II modulates the cortical lifetime of the actin crosslinker α-actinin, which in turn tunes actin filament dynamics, thereby controlling furrow ingression.

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M3 - Short survey

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JO - Developmental Cell

JF - Developmental Cell

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ER -

Putting the Brakes on Cytokinesis with α-Actinin

Abstract

ASJC Scopus subject areas

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