Putative contributors to the secular increase in obesity: Exploring the roads less traveled

S. W. Keith, D. T. Redden, P. T. Katzmarzyk, M. M. Boggiano, E. C. Hanlon, R. M. Benca, D. Ruden, A. Pietrobelli, J. L. Barger, K. R. Fontaine, C. Wang, L. J. Aronne, S. M. Wright, M. Baskin, N. V. Dhurandhar, M. C. Lijoi, C. M. Grilo, M. DeLuca, A. O. Westfall, D. B. Allison

Research output: Contribution to journalArticlepeer-review

425 Scopus citations


Objective: To investigate plausible contributors to the obesity epidemic beyond the two most commonly suggested factors, reduced physical activity and food marketing practices. Design: A narrative review of data and published materials that provide evidence of the role of additional putative factors in contributing to the increasing prevalence of obesity. Data: Information was drawn from ecological and epidemiological studies of humans, animal studies and studies addressing physiological mechanisms, when available. Results: For at least 10 putative additional explanations for the increased prevalence of obesity over the recent decades, we found supportive (although not conclusive) evidence that in many cases is as compelling as the evidence for more commonly discussed putative explanations. Conclusion: Undue attention has been devoted to reduced physical activity and food marketing practices as postulated causes for increases in the prevalence of obesity, leading to neglect of other plausible mechanisms and well-intentioned, but potentially ill-founded proposals for reducing obesity rates.

Original languageEnglish (US)
Pages (from-to)1585-1594
Number of pages10
JournalInternational Journal of Obesity
Issue number11
StatePublished - Oct 25 2006


  • Additional explanations
  • Body mass index
  • Food marketing
  • Obesity epidemic
  • Physical activity
  • Prevalence of obesity

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Food Science
  • Endocrinology, Diabetes and Metabolism


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