Purple Glove Syndrome after Phenytoin or Fosphenytoin Administration: Review of Reported Cases and Recommendations for Prevention

Medicine & Life Sciences

• fosphenytoin 81%
• Phenytoin 53%
• Extremities 13%
• Injection Site Reaction 13%
• Thrombosis 7%
• Ischemia 7%
• Fasciotomy 6%
• Hyaluronoglucosaminidase 6%
• Gray Literature 5%
• Skin Transplantation 5%
• Thrombectomy 5%
• Conduction Anesthesia 5%
• Blood Vessels 5%
• Skin 5%
• Debridement 4%
• Vasodilator Agents 4%
• Amputation 4%
• Venous Thrombosis 4%
• Anticonvulsants 4%
• Anticoagulants 4%
• Heparin 4%
• Cold Temperature 4%
• MEDLINE 4%
• Veins 3%
• Angiography 3%
• Language 3%
• Statistics 3%
• Hot Temperature 3%
• Hand 3%
• Perfusion 3%
• Anti-Bacterial Agents 3%
• Guidelines 3%
• Morbidity 2%
• Injections 2%
• Wounds and Injuries 2%
• Therapeutics 1%

Chemical Compounds

• Fosphenytoin 100%
• Phenytoin 63%
• Parenteral 30%
• Anticoagulant 14%
• Anticonvulsant 13%
• Heparin 12%
• Dose 9%
• Heat 8%
• Antimicrobial Agent 8%
• Time 4%
• Application 3%