Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats

Chad R. Gordon; Daniel R. Lefebvre; Martha S. Matthews; Louise F. Strande; Steven W. Marra; Massimiliano Guglielmi; Jad Skaf; Steven M. Hollenberg; Charles W. Hewitt

doi:10.1002/micr.20343

Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats

Chad R. Gordon, Daniel R. Lefebvre, Martha S. Matthews, Louise F. Strande, Steven W. Marra, Massimiliano Guglielmi, Jad Skaf, Steven M. Hollenberg, Charles W. Hewitt

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Noninvasive assessment of heterotopic heart transplants using Doppler echocardiography was first described in two patients by Allen at Stanford in 1981. Since then, numerous experiments studying heterotopic heart transplantation in humans and large animals have confirmed its utility by employing either an intra-abdominal or cervical model. In rats, however, prior research investigating intra-abdominal heterotopic hearts has showed echocardiography to be ineffective. We have recently developed a new technique for heterotopic femoral heart transplantation in rats, which employs the novel use of trans-femoral echocardiography. Therefore, our goal was to re-examine the efficacy of echocardiography for detection of graft rejection.

Original language	English (US)
Pages (from-to)	240-244
Number of pages	5
Journal	Microsurgery
Volume	27
Issue number	4
DOIs	https://doi.org/10.1002/micr.20343
State	Published - 2007
Externally published	Yes

ASJC Scopus subject areas

Surgery

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title = "Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats",

abstract = "Noninvasive assessment of heterotopic heart transplants using Doppler echocardiography was first described in two patients by Allen at Stanford in 1981. Since then, numerous experiments studying heterotopic heart transplantation in humans and large animals have confirmed its utility by employing either an intra-abdominal or cervical model. In rats, however, prior research investigating intra-abdominal heterotopic hearts has showed echocardiography to be ineffective. We have recently developed a new technique for heterotopic femoral heart transplantation in rats, which employs the novel use of trans-femoral echocardiography. Therefore, our goal was to re-examine the efficacy of echocardiography for detection of graft rejection.",

author = "Gordon, {Chad R.} and Lefebvre, {Daniel R.} and Matthews, {Martha S.} and Strande, {Louise F.} and Marra, {Steven W.} and Massimiliano Guglielmi and Jad Skaf and Hollenberg, {Steven M.} and Hewitt, {Charles W.}",

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language = "English (US)",

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T1 - Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats

AU - Gordon, Chad R.

AU - Lefebvre, Daniel R.

AU - Matthews, Martha S.

AU - Strande, Louise F.

AU - Marra, Steven W.

AU - Guglielmi, Massimiliano

AU - Skaf, Jad

AU - Hollenberg, Steven M.

AU - Hewitt, Charles W.

PY - 2007

Y1 - 2007

N2 - Noninvasive assessment of heterotopic heart transplants using Doppler echocardiography was first described in two patients by Allen at Stanford in 1981. Since then, numerous experiments studying heterotopic heart transplantation in humans and large animals have confirmed its utility by employing either an intra-abdominal or cervical model. In rats, however, prior research investigating intra-abdominal heterotopic hearts has showed echocardiography to be ineffective. We have recently developed a new technique for heterotopic femoral heart transplantation in rats, which employs the novel use of trans-femoral echocardiography. Therefore, our goal was to re-examine the efficacy of echocardiography for detection of graft rejection.

AB - Noninvasive assessment of heterotopic heart transplants using Doppler echocardiography was first described in two patients by Allen at Stanford in 1981. Since then, numerous experiments studying heterotopic heart transplantation in humans and large animals have confirmed its utility by employing either an intra-abdominal or cervical model. In rats, however, prior research investigating intra-abdominal heterotopic hearts has showed echocardiography to be ineffective. We have recently developed a new technique for heterotopic femoral heart transplantation in rats, which employs the novel use of trans-femoral echocardiography. Therefore, our goal was to re-examine the efficacy of echocardiography for detection of graft rejection.

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JO - Microsurgery

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Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats

Abstract

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