TY - JOUR
T1 - Pulmonary function in children with a history of laryngotracheobronchitis
AU - Loughlin, Gerald M.
AU - Taussig, Lynn M.
N1 - Funding Information:
From the Pediatric Pulmonary Section, Department of Pediatrics, Division of Respiratory Sciences (Westend Laboratories), University of A rbona, Arizona Health Sciences Center. Supported in part by a Young Investigator Grant (Dr. Taussig) HL 17153 and by a Specialized Center of Research Grant HL 14136, from the National Heart, Lung, and Blood Institute. Presented, in part, at the annual meeting of The Western Society For Pediatric Research, Carmel, California, 1977. *Recipient of a Fellowshipf rom the American Lung Association. **Reprint address: Department of Pediatrics, Arizona Health Sciences Center, Tucson, AZ85724.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1979/3
Y1 - 1979/3
N2 - Baseline, postexercise, and postisoproterenol lung function was studied in 27 children, 8 to 18 years of age, with a past history of laryngotracheobronchitis (croup) and in ten children without such a history. The LTB subjects were divided into two groups, based on the presence or absence of allergies. Baseline flow tests were similar in all groups but small airway function was mildly abnormal in several members of each group. There was no consistent response to isoproterenol inhalation among those who had had croup and normal subjects. Following exercise, however, a significant (P<0.05) number of subjects (14 of 27) in both LTB groups demonstrated bronchoconstriction with a greater than 10% drop in peak expiratory flows. From these studies, it appears that children with a past history of croup have a higher prevalence of increased bronchial reactivity, which occurs irrespective of allergy and baseline lung function abnormalities.
AB - Baseline, postexercise, and postisoproterenol lung function was studied in 27 children, 8 to 18 years of age, with a past history of laryngotracheobronchitis (croup) and in ten children without such a history. The LTB subjects were divided into two groups, based on the presence or absence of allergies. Baseline flow tests were similar in all groups but small airway function was mildly abnormal in several members of each group. There was no consistent response to isoproterenol inhalation among those who had had croup and normal subjects. Following exercise, however, a significant (P<0.05) number of subjects (14 of 27) in both LTB groups demonstrated bronchoconstriction with a greater than 10% drop in peak expiratory flows. From these studies, it appears that children with a past history of croup have a higher prevalence of increased bronchial reactivity, which occurs irrespective of allergy and baseline lung function abnormalities.
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U2 - 10.1016/S0022-3476(79)80572-7
DO - 10.1016/S0022-3476(79)80572-7
M3 - Article
C2 - 423015
AN - SCOPUS:0018373526
SN - 0022-3476
VL - 94
SP - 365
EP - 369
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 3
ER -