Psychiatric Medication Use in Pregnancy and Breastfeeding

Jennifer L. Payne

Research output: Contribution to journalReview articlepeer-review


Active peripartum psychiatric illness is associated with adverse outcomes for exposed pregnancies/children. Likely due to high rates of obesity, pregnant women with psychiatric illness also have higher rates of preeclampsia, cesarean section, and gestational diabetes. Postpartum depression is associated with lower IQ, slower language development, and behavioral problems in exposed children. Discontinuing psychiatric medications for pregnancy increases risk for relapse significantly, and the postpartum time period is high risk for developing psychiatric illness. Obstetricians-gynecologists are front-line providers for psychiatric care of women during peripartum. This article provides a framework and knowledge base for management of psychiatric illness during peripartum.

Original languageEnglish (US)
Pages (from-to)131-149
Number of pages19
JournalObstetrics and Gynecology Clinics of North America
Issue number1
StatePublished - Mar 2021


  • Antidepressants
  • Breastfeeding
  • Mood stabilizers
  • Postpartum depression
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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