@article{3c4d263ecd3d478eaec279ddca9544a7,
title = "Psychiatric Disorders in the Parents of Autistic Individuals",
abstract = "Eighty-one parents of 42 autistic probands and 34 parents of 18 Down syndrome probands were examined using a semistructured, investigator-based version of the Schedule for Affective Disorders and Schizophrenia Lifetime Version to estimate the lifetime risk of psychiatric disorder. The lifetime prevalence rate of anxiety disorder was significantly greater in parents of autistic probands than in parents of Down syndrome probands. The lifetime prevalence rate of major depressive disorder, while not significantly different in cases and controls, may be high in the parents of autistic probands (27%) in comparison with populations rates.",
keywords = "anxiety disorder, autism, genetics, major depressive disorder, stress",
author = "JOSEPH PIVEN and CHASE, {GARY A.} and REBECCA LANDA and MARYANN WZOREK and JEANNE GAYLE and DELORES CLOUD and SUSAN FOLSTEIN",
note = "Funding Information: Accepted September 17, 1990. Drs. Piven and Landa are Assistant Professors of Psychiatry, Dr. Folstein is Professor ofPsychiatry, Ms. Wzorek and Ms. Gayle are Research Associates, and Ms. Cloud is Research Programmer, The Johns Hopkins University, School of Medicine, Department of Psychiatry, Baltimore. MD. Dr. Chase is Professor ofMental Hygiene, The Johns Hopkins University School of Hygiene and Public Health, Department of Mental Hygiene, Baltimore, MD. This research was supported by NIMH Gram ROI MH39936-04 (Dr. Folstein) and The John Merck Fund (Dr. Piven). The authors are grateful to Marshal Folstein, M.D., and Alan Romanoski, M.D., for reviewing this manuscript and to Cindy Taylor for her assistance in its preparation. Reprint requests to Dr. Piven, Assistant Professor, Psychiatry, University of Iowa Hospital and Clinics, Child Psychiatry, 650 Newton Road, Iowa City, 1A 52242.",
year = "1991",
doi = "10.1097/00004583-199105000-00019",
language = "English (US)",
volume = "30",
pages = "471--478",
journal = "Journal of the American Academy of Child and Adolescent Psychiatry",
issn = "0890-8567",
publisher = "Elsevier Inc.",
number = "3",
}