Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

Keyphrases

• Genome-wide Association Study 100%
• Immune-mediated Diseases 100%
• Genomic Regions 100%
• Crohn's Disease 66%
• Rheumatologic Diseases 66%
• Complex Disease 66%
• Mendelian Disease 66%
• Complex Traits 33%
• Genetic Association 33%
• In(III) 33%
• Risk Loci 33%
• Risk Variant 33%
• Disease-associated 33%
• Encoded Protein 33%
• Protein-protein Interaction Network 33%
• Interacting Proteins 33%
• Non-immune 33%
• Type 2 Diabetes Mellitus (T2DM) 33%
• Lipid Levels 33%
• Region Encoding 33%
• Physical Interaction 33%
• Predictive Power 33%
• Disease Biology 33%
• Associated Genes 33%
• Molecular Processes 33%
• Biological Relevance 33%
• Causal mutation 33%
• Permutation Method 33%
• Disease Network 33%
• Connected Network 33%
• Disease Genome 33%
• Densely Connected 33%
• Immune Phenotype 33%
• Protein Products 33%
• Height Level 33%

Immunology and Microbiology

• Genome-Wide Association Study 100%
• Inflammatory Arthritis 66%
• Crohn's Disease 66%
• Genetic Association 33%
• Lipid Level 33%
• Protein-Protein Interaction Networks 33%

Biochemistry, Genetics and Molecular Biology

• Genome-Wide Association Study 100%
• Genomics 100%
• Genetic Association 33%
• Lipid Level 33%
• Protein-Protein Interaction Networks 33%
• Maturity Onset Diabetes of the Young 33%