TY - JOUR
T1 - Protection from Shigella sonnei infection by immunisation of rabbits with Plesiomonas shigelloides (SVC 01)
AU - Sayeed, S.
AU - Sack, D. A.
AU - Qadri, F.
PY - 1992
Y1 - 1992
N2 - Plesiomonas shigelloides, an organism commonly found in water, is only rarely associated with diarrhoea in man. P. shigelloides serotype O:17 (SVC O1), which is antigenically similar to Shigella sonnei, was found to be neither virulent nor toxic for rabbits. Rabbits immunised by feeding with P. shigelloides (SVC O1) were completely protected against an oral challenge with 1010 cells of S. sonnei but non-immunised rabbits were not. P. shigelloides (SVC O1) may be a useful vaccine strain for shigellosis.
AB - Plesiomonas shigelloides, an organism commonly found in water, is only rarely associated with diarrhoea in man. P. shigelloides serotype O:17 (SVC O1), which is antigenically similar to Shigella sonnei, was found to be neither virulent nor toxic for rabbits. Rabbits immunised by feeding with P. shigelloides (SVC O1) were completely protected against an oral challenge with 1010 cells of S. sonnei but non-immunised rabbits were not. P. shigelloides (SVC O1) may be a useful vaccine strain for shigellosis.
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U2 - 10.1099/00222615-37-6-382
DO - 10.1099/00222615-37-6-382
M3 - Article
C2 - 1460657
AN - SCOPUS:0026724403
SN - 0022-2615
VL - 37
SP - 382
EP - 384
JO - Journal of medical microbiology
JF - Journal of medical microbiology
IS - 6
ER -