Prospects for a novel ultrashort pulsed laser technology for pathogen inactivation

Shaw Wei D. Tsen, Tzyy Choou Wu, Juliann G. Kiang, Kong Thon Tsen

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations


The threat of emerging pathogens and microbial drug resistance has spurred tremendous efforts to develop new and more effective antimicrobial strategies. Recently, a novel ultrashort pulsed (USP) laser technology has been developed that enables efficient and chemical-free inactivation of a wide spectrum of viral and bacterial pathogens. Such a technology circumvents the need to introduce potentially toxic chemicals and could permit safe and environmentally friendly pathogen reduction, with a multitude of possible applications including the sterilization of pharmaceuticals and blood products, and the generation of attenuated or inactivated vaccines.

Original languageEnglish (US)
Article number62
JournalJournal of biomedical science
Issue number1
StatePublished - 2012

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Clinical Biochemistry
  • Cell Biology
  • Biochemistry, medical
  • Pharmacology (medical)


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