Abstract
Biopsies of 17 peptic ulcer patients, randomly treated by partial gastrectomy with either Billroth-II (n = 9) or Roux-en-Y (n = 8) anastomosis were studied before and six months after surgery to determine the role of bile reflux in the early postoperative histological alterations of the gastric mucosa. After BII-gastrectomy bile acid reflux (median 16.1 μmol/h) was significantly higher (p <0.0001) than after RY-gastrectomy (0.1 μmol/h). Campylobacter pylori was present in the preoperative biopsies of all 17 patients. After RY-gastrectomy biopsies of all eight patients were positive for Campylobacter pylori, but was detected in only five of the nine patients with BII-gastrectomy. Properative scores of gastritis grading were similar in both groups and no significant differences were found postoperatively. Gastritis scores of the anastomotic mucosa in patients with BII-gastrectomy were significantly higher (p
Original language | English (US) |
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Pages (from-to) | 1552-1557 |
Number of pages | 6 |
Journal | Gut |
Volume | 30 |
Issue number | 11 |
State | Published - 1989 |
Externally published | Yes |
ASJC Scopus subject areas
- Gastroenterology