Prophylactic Granulocyte Transfusion during Chemotherapy for Acute Myelogenous Leukemia

Toronto Leukemia Study Group

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


To the Editor: Despite the reservations mentioned by Higby in an accompanying editorial,1 the study by Strauss and his colleagues2 (September 10 issue) provides convincing evidence that prophylactic granulocyte transfusions should not be used routinely during remission-induction therapy of acute myelogenous leukemia (AML). The Toronto Leukemia Study Group recently completed an investigation, similar to that of Strauss et al., of the role of prophylactic granulocyte transfusions in adults with acute nonlymphocytic leukemia. Sixty-seven patients were randomized to a prophylactic granulocyte transfusion or to a control group. Patients in both groups received standard remission-induction chemotherapy. (During the initial part of.

Original languageEnglish (US)
Pages (from-to)46-48
Number of pages3
JournalNew England Journal of Medicine
Issue number1
StatePublished - Jan 7 1982

ASJC Scopus subject areas

  • General Medicine


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