Prophylactic Antibiotics and Prevention of Surgical Site Infections

Peter A. Najjar, Douglas S. Smink

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations


Healthcare-associated infections present a significant source of preventable morbidity and mortality. More than 30% of all healthcare-associated infections are represented by surgical site infections, making them the most common subtype. Studies suggest that 40% to 60% of these infections are preventable, yet many hospitals have yet to implement evidence-based best practices. This article reviews the impact of surgical site infections, describes their measurement and reporting, and most importantly provides perioperative strategies for their prevention with a focus on the appropriate use of prophylactic antibiotics.

Original languageEnglish (US)
Pages (from-to)269-283
Number of pages15
JournalSurgical Clinics of North America
Issue number2
StatePublished - Apr 1 2015
Externally publishedYes


  • Perioperative infection control
  • Prophylactic antibiotics
  • Surgical site infection

ASJC Scopus subject areas

  • Surgery


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