PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN

Joyce A. Benjamins; G. M. McKhann

doi:10.1111/j.1471-4159.1973.tb00082.x

PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN

Joyce A. Benjamins, G. M. McKhann

Krieger School of Arts and Sciences

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Abstract— Choline and ethanolamine phospholipids in the 105,000 g supernatant fraction of rat brain exhibited density and electrophoretic properties consistent with their binding to protein. About 40% of these two phospholipids were bound to soluble lipoproteins, whereas the remainder appeared to be associated with particulate complexes. Following intracranial injection of [2‐³H]glycerol, the specific radioactivities of the choline and ethanolamine phospholipids in the supernatant fraction were higher than those in the microsomal fraction at all time points examined, from 15 min to 12 h after injection. The properties of cytoplasmic lipoproteins containing choline and ethanolamine phospholipids have been compared with those which we have previously described containing sulphatide.

Original language	English (US)
Pages (from-to)	1121-1129
Number of pages	9
Journal	Journal of Neurochemistry
Volume	20
Issue number	4
DOIs	https://doi.org/10.1111/j.1471-4159.1973.tb00082.x
State	Published - Apr 1973

ASJC Scopus subject areas

Biochemistry
Cellular and Molecular Neuroscience

Access to Document

10.1111/j.1471-4159.1973.tb00082.x

Cite this

@article{e36afc58154b45b097c4e01d1b68c43b,

title = "PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN",

abstract = "Abstract— Choline and ethanolamine phospholipids in the 105,000 g supernatant fraction of rat brain exhibited density and electrophoretic properties consistent with their binding to protein. About 40% of these two phospholipids were bound to soluble lipoproteins, whereas the remainder appeared to be associated with particulate complexes. Following intracranial injection of [2‐3H]glycerol, the specific radioactivities of the choline and ethanolamine phospholipids in the supernatant fraction were higher than those in the microsomal fraction at all time points examined, from 15 min to 12 h after injection. The properties of cytoplasmic lipoproteins containing choline and ethanolamine phospholipids have been compared with those which we have previously described containing sulphatide.",

author = "Benjamins, {Joyce A.} and McKhann, {G. M.}",

year = "1973",

month = apr,

doi = "10.1111/j.1471-4159.1973.tb00082.x",

language = "English (US)",

volume = "20",

pages = "1121--1129",

journal = "Journal of Neurochemistry",

issn = "0022-3042",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN

AU - Benjamins, Joyce A.

AU - McKhann, G. M.

PY - 1973/4

Y1 - 1973/4

N2 - Abstract— Choline and ethanolamine phospholipids in the 105,000 g supernatant fraction of rat brain exhibited density and electrophoretic properties consistent with their binding to protein. About 40% of these two phospholipids were bound to soluble lipoproteins, whereas the remainder appeared to be associated with particulate complexes. Following intracranial injection of [2‐3H]glycerol, the specific radioactivities of the choline and ethanolamine phospholipids in the supernatant fraction were higher than those in the microsomal fraction at all time points examined, from 15 min to 12 h after injection. The properties of cytoplasmic lipoproteins containing choline and ethanolamine phospholipids have been compared with those which we have previously described containing sulphatide.

AB - Abstract— Choline and ethanolamine phospholipids in the 105,000 g supernatant fraction of rat brain exhibited density and electrophoretic properties consistent with their binding to protein. About 40% of these two phospholipids were bound to soluble lipoproteins, whereas the remainder appeared to be associated with particulate complexes. Following intracranial injection of [2‐3H]glycerol, the specific radioactivities of the choline and ethanolamine phospholipids in the supernatant fraction were higher than those in the microsomal fraction at all time points examined, from 15 min to 12 h after injection. The properties of cytoplasmic lipoproteins containing choline and ethanolamine phospholipids have been compared with those which we have previously described containing sulphatide.

UR - http://www.scopus.com/inward/record.url?scp=0015607568&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015607568&partnerID=8YFLogxK

U2 - 10.1111/j.1471-4159.1973.tb00082.x

DO - 10.1111/j.1471-4159.1973.tb00082.x

M3 - Article

C2 - 4697874

AN - SCOPUS:0015607568

SN - 0022-3042

VL - 20

SP - 1121

EP - 1129

JO - Journal of Neurochemistry

JF - Journal of Neurochemistry

IS - 4

ER -

PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this