TY - GEN
T1 - Propagation wavefronts in two-dimensional topologies of cardiac cell networks
AU - Fishler, Matthew G.
AU - Thakor, Nitish V.
AU - Reidt, Philip
N1 - Publisher Copyright:
© 1992 IEEE.
PY - 1992
Y1 - 1992
N2 - We present a computer model, implemented on a Cray-2 supercomputer, to explore the role of the discontinuous, nonuniform, and anisotropic cellular structure of cardiac tissue on normal propagation patterns. For this study, we hold cell shape constant and evaluate planar propagation wavefronts oriented longitudinally and transversely to the cell axis for two different tissue topologies-rectangular and brick-like-and for different degrees of transverse coupling strengths between cells. Nonuniformity is introduced into the model via spatial dispersions of coupling strengths. Even under severe conditions of uncoupling, both topologies show remarkable abilities in maintaining a uniformly planar wavefront. Thus, our simulations suggest that cardiac cell networks are very robust in their abilities to equilibrate electrical spatial inhomogeneities, even in the face of significant structural and coupling inhomogeneities.
AB - We present a computer model, implemented on a Cray-2 supercomputer, to explore the role of the discontinuous, nonuniform, and anisotropic cellular structure of cardiac tissue on normal propagation patterns. For this study, we hold cell shape constant and evaluate planar propagation wavefronts oriented longitudinally and transversely to the cell axis for two different tissue topologies-rectangular and brick-like-and for different degrees of transverse coupling strengths between cells. Nonuniformity is introduced into the model via spatial dispersions of coupling strengths. Even under severe conditions of uncoupling, both topologies show remarkable abilities in maintaining a uniformly planar wavefront. Thus, our simulations suggest that cardiac cell networks are very robust in their abilities to equilibrate electrical spatial inhomogeneities, even in the face of significant structural and coupling inhomogeneities.
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U2 - 10.1109/CIC.1992.269501
DO - 10.1109/CIC.1992.269501
M3 - Conference contribution
AN - SCOPUS:84944296669
T3 - Proceedings - Computers in Cardiology, CIC 1992
SP - 411
EP - 414
BT - Proceedings - Computers in Cardiology, CIC 1992
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 1992 IEEE Conference on Computers in Cardiology, CIC 1992
Y2 - 11 October 1992 through 14 October 1992
ER -