Prolonged Remission of Tumor-Stage Mycosis Fungoides by Topical Immunotherapy

Eric C. Vonderheid, Daniel L. Dellatorre, Eugene J. Van Scott

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A patient with slowly progressive tumor-stage mycosis fungoides (MF), without apparent extracutaneous involvement, received topical immunotherapy with mechlorethamine hydrochloride as the immunogen. A complete remission was achieved after two months of treatment, and the patient has remained free of detectable disease without further treatment for more than seven years. This case is also unusual in that, before treatment, a temporary exacerbation of MF had occurred during three pregnancies. These observations suggest that the natural resistance against the progression of MF in this patient was enhanced by immunotherapy. (Arch Dermatol 1981;117:586-589).

Original languageEnglish (US)
Pages (from-to)586-589
Number of pages4
JournalArchives of Dermatology
Issue number9
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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