Proline biosynthesis and degradation in mammalian cells and tissue

J. M. Phang, D. Valle, E. M. Kowaloff

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Radioisotopic assays were developed for the enzymes of proline metabolism. These assays are specific and sensitive enough to measure enzyme activities in cultured cells and biopsy specimens. Measurements of these enzymes in tissues and cultured cells suggest that endogenous biosynthesis of proline may be an important source of this amino acid.

Original languageEnglish (US)
Pages (from-to)298-302
Number of pages5
JournalAnnals of Clinical and Laboratory Science
Issue number4
StatePublished - Dec 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology


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