TY - JOUR
T1 - Prognostic significance of alkaline phosphatase measurements in patients with osteogenic sarcoma receiving chemotherapy
AU - Thorpe, William P.
AU - Reilly, James J.
AU - Rosenberg, Steven A.
PY - 1979/6
Y1 - 1979/6
N2 - During the period January 1975 to August 1977, alkaline phosphatase levels in 30 patients with osteogenic sarcoma were closely followed in an attempt to determine if these measurements had clinical value in predicting the course of patients with this disease. Of 17 patients with elevated preoperative alkaline phosphatase levels, 12 recurred. Of 13 patients with normal preoperative alkaline phosphatase levels, only 4 recurred (p <.05). Thus, alkaline phosphatase levels that were elevated preoperatively were correlated with poor prognosis. A similar correlation between postoperative alkaline phosphatase levels and prognosis could not be made.
AB - During the period January 1975 to August 1977, alkaline phosphatase levels in 30 patients with osteogenic sarcoma were closely followed in an attempt to determine if these measurements had clinical value in predicting the course of patients with this disease. Of 17 patients with elevated preoperative alkaline phosphatase levels, 12 recurred. Of 13 patients with normal preoperative alkaline phosphatase levels, only 4 recurred (p <.05). Thus, alkaline phosphatase levels that were elevated preoperatively were correlated with poor prognosis. A similar correlation between postoperative alkaline phosphatase levels and prognosis could not be made.
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U2 - 10.1002/1097-0142(197906)43:6<2178::AID-CNCR2820430603>3.0.CO;2-9
DO - 10.1002/1097-0142(197906)43:6<2178::AID-CNCR2820430603>3.0.CO;2-9
M3 - Article
C2 - 287547
AN - SCOPUS:0018650260
SN - 0008-543X
VL - 43
SP - 2178
EP - 2181
JO - Cancer
JF - Cancer
IS - 6
ER -