Profound Hypercalcemia Associated with Acute Toxic-Metabolic Encephalopathy after Calcium Sulfate Bead Use: A Case Report

Samir Sabharwal; Jessica Schmerler; Savyasachi C. Thakkar

doi:10.2106/JBJS.CC.22.00052

Profound Hypercalcemia Associated with Acute Toxic-Metabolic Encephalopathy after Calcium Sulfate Bead Use: A Case Report

Samir Sabharwal, Jessica Schmerler, Savyasachi C. Thakkar

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Case:We present the case of an 81-year-old woman who developed profound hypercalcemia requiring admission to the intensive care unit after calcium sulfate bead use during revision hip arthroplasty. The patient's serum calcium level peaked at 21.0 mg/dL and was associated with acute encephalopathy. After treatment with calcitonin and bisphosphonates, her serum calcium level normalized and her mentation improved.Conclusion:The risk of clinically significant hypercalcemia should be considered when using calcium sulfate during orthopaedic surgery.

Original language	English (US)
Article number	00052
Journal	JBJS case connector
Volume	12
Issue number	1
DOIs	https://doi.org/10.2106/JBJS.CC.22.00052
State	Published - Mar 23 2022

Keywords

calcium sulfate
hypercalcemia
revision arthroplasty

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.2106/JBJS.CC.22.00052

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abstract = "Case:We present the case of an 81-year-old woman who developed profound hypercalcemia requiring admission to the intensive care unit after calcium sulfate bead use during revision hip arthroplasty. The patient's serum calcium level peaked at 21.0 mg/dL and was associated with acute encephalopathy. After treatment with calcitonin and bisphosphonates, her serum calcium level normalized and her mentation improved.Conclusion:The risk of clinically significant hypercalcemia should be considered when using calcium sulfate during orthopaedic surgery.",

keywords = "calcium sulfate, hypercalcemia, revision arthroplasty",

author = "Samir Sabharwal and Jessica Schmerler and Thakkar, {Savyasachi C.}",

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PY - 2022/3/23

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AB - Case:We present the case of an 81-year-old woman who developed profound hypercalcemia requiring admission to the intensive care unit after calcium sulfate bead use during revision hip arthroplasty. The patient's serum calcium level peaked at 21.0 mg/dL and was associated with acute encephalopathy. After treatment with calcitonin and bisphosphonates, her serum calcium level normalized and her mentation improved.Conclusion:The risk of clinically significant hypercalcemia should be considered when using calcium sulfate during orthopaedic surgery.

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Profound Hypercalcemia Associated with Acute Toxic-Metabolic Encephalopathy after Calcium Sulfate Bead Use: A Case Report

Abstract

Keywords

ASJC Scopus subject areas

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