Probing nanoscopic cell surface areas for rapid and labelfree plasmon enhanced Raman detection

Chi Zhang; Soumik Siddhanta; Chao Zheng; Ishan Barman

doi:10.1364/TRANSLATIONAL.2016.JM3A.53

Probing nanoscopic cell surface areas for rapid and labelfree plasmon enhanced Raman detection

Chi Zhang
, Soumik Siddhanta
, Chao Zheng
, Ishan Barman

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Surface enhanced Raman spectroscopy (SERS) is an emerging nanoscale tool for small quality sample probing. Its highly localized detection range makes it suits for cell membrane composition research. In this research, we combined SERS with nanopillar array to identify aggressive prostate cancer cell surface markers. Inherent signal fluctuations emanating from cell lines with differential biomarker expression highlight the potential of using such a nanopillar-based platform for probing the chemical and mechanical phenotype and pave the way for evolution of a direct and label free assessment of cancer membrane biomarkers.

Original language	English (US)
Title of host publication	Clinical and Translational Biophotonics, Translational 2016
Publisher	Optica Publishing Group (formerly OSA)
ISBN (Print)	9781943580101
DOIs	https://doi.org/10.1364/TRANSLATIONAL.2016.JM3A.53
State	Published - Apr 18 2016
Externally published	Yes
Event	Clinical and Translational Biophotonics, Translational 2016 - Fort Lauderdale, United States Duration: Apr 25 2016 → Apr 28 2016

Publication series

Name	Optics InfoBase Conference Papers
ISSN (Electronic)	2162-2701

Other

Other	Clinical and Translational Biophotonics, Translational 2016
Country/Territory	United States
City	Fort Lauderdale
Period	4/25/16 → 4/28/16

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Mechanics of Materials

Access to Document

10.1364/TRANSLATIONAL.2016.JM3A.53

Cite this

Probing nanoscopic cell surface areas for rapid and labelfree plasmon enhanced Raman detection. / Zhang, Chi; Siddhanta, Soumik; Zheng, Chao et al.
Clinical and Translational Biophotonics, Translational 2016. Optica Publishing Group (formerly OSA), 2016. (Optics InfoBase Conference Papers).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Zhang, C, Siddhanta, S, Zheng, C & Barman, I 2016, Probing nanoscopic cell surface areas for rapid and labelfree plasmon enhanced Raman detection. in Clinical and Translational Biophotonics, Translational 2016. Optics InfoBase Conference Papers, Optica Publishing Group (formerly OSA), Clinical and Translational Biophotonics, Translational 2016, Fort Lauderdale, United States, 4/25/16. https://doi.org/10.1364/TRANSLATIONAL.2016.JM3A.53

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abstract = "Surface enhanced Raman spectroscopy (SERS) is an emerging nanoscale tool for small quality sample probing. Its highly localized detection range makes it suits for cell membrane composition research. In this research, we combined SERS with nanopillar array to identify aggressive prostate cancer cell surface markers. Inherent signal fluctuations emanating from cell lines with differential biomarker expression highlight the potential of using such a nanopillar-based platform for probing the chemical and mechanical phenotype and pave the way for evolution of a direct and label free assessment of cancer membrane biomarkers.",

author = "Chi Zhang and Soumik Siddhanta and Chao Zheng and Ishan Barman",

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Y1 - 2016/4/18

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AB - Surface enhanced Raman spectroscopy (SERS) is an emerging nanoscale tool for small quality sample probing. Its highly localized detection range makes it suits for cell membrane composition research. In this research, we combined SERS with nanopillar array to identify aggressive prostate cancer cell surface markers. Inherent signal fluctuations emanating from cell lines with differential biomarker expression highlight the potential of using such a nanopillar-based platform for probing the chemical and mechanical phenotype and pave the way for evolution of a direct and label free assessment of cancer membrane biomarkers.

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ER -

Probing nanoscopic cell surface areas for rapid and labelfree plasmon enhanced Raman detection

Abstract

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Other

ASJC Scopus subject areas

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