Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE).

Richard C. McEachin; Benjamin J. Keller; Peter P. Zandi; Mohsen Almani; Melvin G. McInnis

Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE).

Richard C. McEachin
, Benjamin J. Keller
, Peter P. Zandi
, Mohsen Almani
, Melvin G. McInnis

Research output: Contribution to journal › Article › peer-review

Abstract

Complex diseases are characterized by multiple genetic and environmental influences on disease susceptibility. Since the multiple genetic influences converge on a single phenotype, some commonality may be evident among genes that influence the disease. We exploit this potential commonality among candidate disease genes to prioritize genes for further analysis and to pose novel, statistically significant, biologically plausible hypotheses on disease etiology.

Original language	English (US)
Pages (from-to)	1068
Number of pages	1
Journal	AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
State	Published - 2007
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE).",

abstract = "Complex diseases are characterized by multiple genetic and environmental influences on disease susceptibility. Since the multiple genetic influences converge on a single phenotype, some commonality may be evident among genes that influence the disease. We exploit this potential commonality among candidate disease genes to prioritize genes for further analysis and to pose novel, statistically significant, biologically plausible hypotheses on disease etiology.",

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journal = "AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium",

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AU - McInnis, Melvin G.

PY - 2007

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AB - Complex diseases are characterized by multiple genetic and environmental influences on disease susceptibility. Since the multiple genetic influences converge on a single phenotype, some commonality may be evident among genes that influence the disease. We exploit this potential commonality among candidate disease genes to prioritize genes for further analysis and to pose novel, statistically significant, biologically plausible hypotheses on disease etiology.

UR - https://www.scopus.com/pages/publications/56149107623

UR - https://www.scopus.com/pages/publications/56149107623#tab=citedBy

M3 - Article

C2 - 18694166

AN - SCOPUS:56149107623

SN - 1559-4076

SP - 1068

JO - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

JF - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

ER -

Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE).

Abstract

ASJC Scopus subject areas

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