Primary tumors of the axial spine

Paul E. Kaloostian, Patricia Zadnik, Daniel M. Sciubba

Research output: Chapter in Book/Report/Conference proceedingChapter


Primary tumors of the spinal column include a variety of pathologies with variable symptoms, outcomes, and treatment. Knowledge of the lesion's pathology is necessary for proper treatment of any patient presenting with a mass in the bony spinal column. Malignant tumors, such as chordomas, plasmacytomas, osteosarcomas and chondrosarcomas require aggressive surgical resection if the goal is curative intent. Adjuvant chemotherapy and radiation may be needed if the margins of the lesion are compromised, and patients should be followed for several years to monitor for tumor recurrence. In contrast , tumors of benign pathology, such as giant cell tumors and aneurismal bone cysts, may present in younger patients. In all patients, pain is the most common symptom. This chapter will review the symptoms, diagnosis and treatment for primary spinal column tumors, with a focus on the current treatment strategies to optimize patient outcomes.

Original languageEnglish (US)
Title of host publicationBone Tumors
Subtitle of host publicationSymptoms, Diagnosis and Treatment
PublisherNova Science Publishers, Inc.
Number of pages10
ISBN (Print)9781626181908
StatePublished - May 1 2013

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine


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