Primary Lymphoma of the Distal Femur Presenting as Spontaneous Deep Vein Thrombosis and Knee Monoarthritis: A Case Report

Hulaimatu B. Jalloh; Shivani Ahlawat; John M. Gross; Adam S. Levin; Richard A. Schaefer

doi:10.2106/JBJS.CC.21.00402

Primary Lymphoma of the Distal Femur Presenting as Spontaneous Deep Vein Thrombosis and Knee Monoarthritis: A Case Report

Hulaimatu B. Jalloh, Shivani Ahlawat, John M. Gross, Adam S. Levin, Richard A. Schaefer

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Case:A 68-year-old man with a history of unprovoked deep vein thrombosis (DVT) presented with recurrent knee effusions after the initiation of anticoagulation. Radiographs showed soft-tissue swelling without a distinct skeletal lesion. Magnetic resonance imaging, however, showed a marrow-replacing process in the distal femur. Subsequent biopsy demonstrated B-cell lymphoma.Conclusion:This is a rare case of a primary lymphoma of bone mimicking synovial disease. It also highlights the fact that an unprovoked DVT may be a harbinger of an undiagnosed underlying malignancy.

Original language	English (US)
Article number	e21.00402
Journal	JBJS case connector
Volume	11
Issue number	3
DOIs	https://doi.org/10.2106/JBJS.CC.21.00402
State	Published - Sep 9 2021

Keywords

B-cell lymphoma
deep vein thrombosis
knee effusion
lymphoma of bone
synovial disease

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.2106/JBJS.CC.21.00402

Cite this

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title = "Primary Lymphoma of the Distal Femur Presenting as Spontaneous Deep Vein Thrombosis and Knee Monoarthritis: A Case Report",

abstract = "Case:A 68-year-old man with a history of unprovoked deep vein thrombosis (DVT) presented with recurrent knee effusions after the initiation of anticoagulation. Radiographs showed soft-tissue swelling without a distinct skeletal lesion. Magnetic resonance imaging, however, showed a marrow-replacing process in the distal femur. Subsequent biopsy demonstrated B-cell lymphoma.Conclusion:This is a rare case of a primary lymphoma of bone mimicking synovial disease. It also highlights the fact that an unprovoked DVT may be a harbinger of an undiagnosed underlying malignancy.",

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T1 - Primary Lymphoma of the Distal Femur Presenting as Spontaneous Deep Vein Thrombosis and Knee Monoarthritis

T2 - A Case Report

AU - Jalloh, Hulaimatu B.

AU - Ahlawat, Shivani

AU - Gross, John M.

AU - Levin, Adam S.

AU - Schaefer, Richard A.

PY - 2021/9/9

Y1 - 2021/9/9

N2 - Case:A 68-year-old man with a history of unprovoked deep vein thrombosis (DVT) presented with recurrent knee effusions after the initiation of anticoagulation. Radiographs showed soft-tissue swelling without a distinct skeletal lesion. Magnetic resonance imaging, however, showed a marrow-replacing process in the distal femur. Subsequent biopsy demonstrated B-cell lymphoma.Conclusion:This is a rare case of a primary lymphoma of bone mimicking synovial disease. It also highlights the fact that an unprovoked DVT may be a harbinger of an undiagnosed underlying malignancy.

AB - Case:A 68-year-old man with a history of unprovoked deep vein thrombosis (DVT) presented with recurrent knee effusions after the initiation of anticoagulation. Radiographs showed soft-tissue swelling without a distinct skeletal lesion. Magnetic resonance imaging, however, showed a marrow-replacing process in the distal femur. Subsequent biopsy demonstrated B-cell lymphoma.Conclusion:This is a rare case of a primary lymphoma of bone mimicking synovial disease. It also highlights the fact that an unprovoked DVT may be a harbinger of an undiagnosed underlying malignancy.

KW - B-cell lymphoma

KW - deep vein thrombosis

KW - knee effusion

KW - lymphoma of bone

KW - synovial disease

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Primary Lymphoma of the Distal Femur Presenting as Spontaneous Deep Vein Thrombosis and Knee Monoarthritis: A Case Report

Abstract

Keywords

ASJC Scopus subject areas

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