Prevalence of Neisseria gonorrhoeae among men screened for Chlamydia trachomatis in four United States Cities, 1999-2003

Charlotte Ann Gaydos, Charlotte Kathleen Kent, Cornelis Arthur Rietmeijer, Nancy Jo Willard, Jeanne Marisa Marrazzo, Johanna Beach Chapin, Eileen Frances Dunne, Lauri Ellen Markowitz, Jeffrey David Klausner, Jonathan Mark Ellen, Julia Ann Schillinger

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


OBJECTIVES: Neisseria gonorrhoeae infections are the second most commonly reported disease in the United States and cause significant morbidity. We describe the prevalence of gonorrhea in a large sample of men tested for gonorrhea and Chlamydia trachomatis in Baltimore, Denver, San Francisco, and Seattle. METHODS: Gonorrhea prevalence was measured among 17,712 men tested in a variety of non-sexually transmitted disease (STD) clinic venues using urine-based nucleic acid amplification tests. RESULTS: Among 16,850 asymptomatic men, prevalence ranged from 0% to 1.5% by city (P = 0.20): Baltimore 1.3%, Denver 1.5%, San Francisco 1.5%, and Seattle 0%. Among 862 symptomatic men, the gonorrhea prevalence varied from 0.0% to 28.3% by city (P <0.01). CONCLUSIONS: The high prevalence of gonorrhea in symptomatic men supports the importance of testing for symptomatic men. The prevalence of gonorrhea among asymptomatic men is low, and routine screening cannot be recommended when screening is performed for chlamydia, unless a substantial local prevalence of gonorrhea can be documented in specific targeted venues or population groups.

Original languageEnglish (US)
Pages (from-to)314-319
Number of pages6
JournalSexually transmitted diseases
Issue number5
StatePublished - May 2006

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases


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