TY - JOUR
T1 - Prevalence of Kaposi's sarcoma in patients with AIDS and associated factors, São Paulo-SP, Brazil, 2003-2010
AU - Tancredi, Mariza Vono
AU - Pinto, Valdir Monteiro
AU - Silva, Mariliza Henrique da
AU - Pimentel, Sidnei Rana
AU - Silva, Tatiana Santana Bueno da
AU - Ito, Sandra Mitie Akamatsu
AU - Golub, Jonathan E.
AU - Toscano, Ana Luiza de Castro Conde
PY - 2017/4/1
Y1 - 2017/4/1
N2 - OBJECTIVE: to estimate the prevalence of Kaposi's sarcoma (KS) in patients with AIDS and identify the associated factors to the occurrence of this neoplasm. METHODS: this is a cross-sectional study with notification data from two AIDS reference centers in São Paulo-SP, Brazil, from January, 2003 to March, 2010; probabilistic linkage and multiple logistic regression methods were applied. RESULTS: among 3,557 AIDS cases, 213 (6%) presented KS; 95.3% of them occurred in males; male sex (OR=3.1; 95%CI=1.4;6.6), age at the AIDS diagnosis >28 years old (OR=1.6; 95%CI=1.0;2.6), MSM (OR=3.2; 95%CI=2.0;4.9), prior use of HAART (OR=0.4; 95%CI=0.3;0.5), AIDS diagnosis between 2007-2010 (OR=0.3; 95%CI=0.2;0.4), and CD4+ T-cell counting under 200cells/mm3 (OR=16.0; 95%CI=6.0;42.7) and 200-500cells/mm³ (OR=2,5; 95%CI=1.1;6.4) were associated to the occurrence of KS. CONCLUSION: KS has a high prevalence in São Paulo-SP; strategies for early HIV diagnosis may reduce this prevalence.
AB - OBJECTIVE: to estimate the prevalence of Kaposi's sarcoma (KS) in patients with AIDS and identify the associated factors to the occurrence of this neoplasm. METHODS: this is a cross-sectional study with notification data from two AIDS reference centers in São Paulo-SP, Brazil, from January, 2003 to March, 2010; probabilistic linkage and multiple logistic regression methods were applied. RESULTS: among 3,557 AIDS cases, 213 (6%) presented KS; 95.3% of them occurred in males; male sex (OR=3.1; 95%CI=1.4;6.6), age at the AIDS diagnosis >28 years old (OR=1.6; 95%CI=1.0;2.6), MSM (OR=3.2; 95%CI=2.0;4.9), prior use of HAART (OR=0.4; 95%CI=0.3;0.5), AIDS diagnosis between 2007-2010 (OR=0.3; 95%CI=0.2;0.4), and CD4+ T-cell counting under 200cells/mm3 (OR=16.0; 95%CI=6.0;42.7) and 200-500cells/mm³ (OR=2,5; 95%CI=1.1;6.4) were associated to the occurrence of KS. CONCLUSION: KS has a high prevalence in São Paulo-SP; strategies for early HIV diagnosis may reduce this prevalence.
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U2 - 10.5123/S1679-49742017000200015
DO - 10.5123/S1679-49742017000200015
M3 - Article
C2 - 28492779
AN - SCOPUS:85058733148
SN - 1679-4974
VL - 26
SP - 379
EP - 387
JO - Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
JF - Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
IS - 2
ER -