Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh

Mustafizur Rahman, Rasheda Sultana, Giasuddin Ahmed, Sharifun Nahar, Zahid M. Hassan, Farjana Saiada, Goutam Podder, Abu S.G. Faruque, A. K. Siddique, David A. Sack, Jelle Matthijnssens, Marc Van Ranst, Tasnim Azim

Research output: Contribution to journalArticlepeer-review

133 Scopus citations


Approximately 20,000 stool specimens from patients with diarrhea visiting 1 urban and 1 rural hospital in Bangladesh during January 2001-May 2006 were tested for group A rotavirus antigen, and 4,712 (24.0%) were positive. G and P genotyping was performed on a subset of 10% of the positive samples (n = 471). During the 2001-2005 rotavirus seasons, G1P[8] (36.4%) and G9P[8] (27.7%) were the dominant strains, but G2[4] and G12P[6] were present in 15.4% and 3.1% of the rotavirus-positive patients, respectively. During the 2005-06 rotavirus season, G2P[4] (43.2%) appeared as the most prevalent strain, and G12P[6] became a more prevalent strain (11.1%) during this season. Because recently licensed rotavirus vaccines include only the P[8] specificity, it is unknown how the vaccines will perform in settings where non-P[8] types are prevalent.

Original languageEnglish (US)
Pages (from-to)18-24
Number of pages7
JournalEmerging infectious diseases
Issue number1
StatePublished - Jan 2007
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases


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